Myristoyl pentapeptide-4
Based on 1 Customer Validation
Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.89%
- CAS 番号: 1392416-25-9
- 分子式: C37H71N7O10
- 分子量:774.00
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
Myristoyl pentapeptide-4 is a synthetic peptide composed of five amino acids with the sequence Lys-Thr-Thr-Lys-Ser (KTTKS)[1].
Myristoyl pentapeptide-4 (10-40 μM, 48 h) specifically targets keratin, activates the transcription and translation of keratin genes, promotes the synthesis of keratin, thereby improving the elasticity and strength of hair[1].
Myristoyl pentapeptide-4 (0-25 μM, 24 h) promotes the proliferation of HaCaT, stimulates the migration of human hair follicle papilla cells (HDPCs)[1].
Myristoyl pentapeptide-4 stimulates skin fibroblasts to produce collagen and fibronectin, thereby reducing wrinkles and improving skin elasticity. Myristoyl pentapeptide-4 also promotes wound healing and skin repair[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HaCaT
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Concentration:0-25 μM
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Incubation Time:24 h
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Result:Improved the cell viability.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Testosterone induced mouse androgenic alopecia (AGA) model[1]
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Dosage:500 μL, the concentration remains unknown, but is related to the concentration range in vitro experiments
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Administration:topical application, once daily for 21 days
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Result:Increasede the the number of hair follicles, and promoted the hair growth.
化学情報
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CAS 番号 1392416-25-9
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性状 Solid
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分子量 774.00
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分子式 C37H71N7O10
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Color White to off-white
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配列
{Myr-Lys}-Thr-Thr-Lys-Ser
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シーケンスの短縮
{Myr-Lys}-TTKS
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (161.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
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- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2920 mL | 6.4599 mL | 12.9199 mL | 32.2997 mL |
| 5 mM | 0.2584 mL | 1.2920 mL | 2.5840 mL | 6.4599 mL | |
| 10 mM | 0.1292 mL | 0.6460 mL | 1.2920 mL | 3.2300 mL | |
| 15 mM | 0.0861 mL | 0.4307 mL | 0.8613 mL | 2.1533 mL | |
| 20 mM | 0.0646 mL | 0.3230 mL | 0.6460 mL | 1.6150 mL | |
| 25 mM | 0.0517 mL | 0.2584 mL | 0.5168 mL | 1.2920 mL | |
| 30 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 1.0767 mL | |
| 40 mM | 0.0323 mL | 0.1615 mL | 0.3230 mL | 0.8075 mL | |
| 50 mM | 0.0258 mL | 0.1292 mL | 0.2584 mL | 0.6460 mL | |
| 60 mM | 0.0215 mL | 0.1077 mL | 0.2153 mL | 0.5383 mL | |
| 80 mM | 0.0161 mL | 0.0807 mL | 0.1615 mL | 0.4037 mL | |
| 100 mM | 0.0129 mL | 0.0646 mL | 0.1292 mL | 0.3230 mL |