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Cat. No.: HY-N3428

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Kamebanin

Kamebanin can be isolated from the leaves of Isodon weisiensis C. Y. Wu. Kamebanin has anti-proliferative activity and can be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 39388-57-3
Formula: C₂₀H₃₀O₄
Molecular Weight:334.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Kamebanin Chemical Structure

CAS No.: 39388-57-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Kamebanin can be isolated from the leaves of Isodon weisiensis C. Y. Wu. Kamebanin has anti-proliferative activity and can be used in cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	7.3 μM Compound: 24	Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay	[PMID: 19072209]
HCT-116	IC₅₀	12 μM Compound: 1	Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth	[PMID: 36690039]
HL-60	IC₅₀	3.3 μM Compound: 1	Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth	[PMID: 36690039]
MCF7	IC₅₀	8.4 μM Compound: 24	Cytotoxicity against human MCF7 cells after 48 hrs by WST-8 assay Cytotoxicity against human MCF7 cells after 48 hrs by WST-8 assay	[PMID: 19072209]
NB-4	IC₅₀	0.9 μM Compound: 24	Cytotoxicity against human NB4 cells after 48 hrs by WST-8 assay Cytotoxicity against human NB4 cells after 48 hrs by WST-8 assay	[PMID: 19072209]
P388	IC₅₀	0.69 μg/mL Compound: 9	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 15043413]
PC-3	IC₅₀	>10 μM Compound: 24	Cytotoxicity against human PC3 cells after 48 hrs by WST-8 assay Cytotoxicity against human PC3 cells after 48 hrs by WST-8 assay	[PMID: 19072209]
SH-SY5Y	IC₅₀	8.9 μM Compound: 24	Cytotoxicity against human SH-SY5Y cells after 48 hrs by WST-8 assay Cytotoxicity against human SH-SY5Y cells after 48 hrs by WST-8 assay	[PMID: 19072209]

Chemical Information

CAS No. 39388-57-3
Molecular Weight 334.45
Formula C₂₀H₃₀O₄
SMILES

O[C@H]1[C@](C2=O)([C@@H](C[C@]3([H])C4(C)C)O)[C@](CC[C@@]1([H])C2=C)([H])[C@@]3([C@H](CC4)O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ding L, et al. Isolation, characterization and crystal structure of cytotoxic ent-kaurane diterpenoids from Isodon weisiensis CY Wu[J]. Zeitschrift für Naturforschung B, 2005, 60(7): 805-810.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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