1. Academic Validation
  2. Intravenous use of cephradine and cefazolin against serious infections

Intravenous use of cephradine and cefazolin against serious infections

  • Antimicrob Agents Chemother. 1979 Jan;15(1):119-22. doi: 10.1128/AAC.15.1.119.
D L Caloza Jr R W Semar G E Bernfeld
Abstract

The relative efficacy and safety of cephradine and cefazolin were compared in 180 patients with a variety of serious infections caused by susceptible organisms. The patients were randomly assigned to one of two groups of 90 patients each. Most patients received 2 to 4 g per day, administered by intravenous injection in four equally divided doses, for a minimum of 4 days. Based on the clinical and microbiological results, the two cephalosporins were found to be comparable in therapeutic effectiveness. Toxicity was not a problem with either drug.

Figures
Products