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Referencia número: HY-185373

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Paclitaxel liposome

Name: Paclitaxel liposome
Brand: MedChemExpress
SKU: HY-185373
Price: 284.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Liposomal paclitaxel)

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Based on 1 Customer Validation

Paclitaxel liposome (Liposomal paclitaxel) is a liposome-encapsulated form of Paclitaxel (HY-B0015). Paclitaxel is a natural antitumor agent that stabilizes tubulin polymerization. Paclitaxel liposome exhibits reduced acute toxicity, prolonged circulating half-life of paclitaxel, and enhanced accumulation at tumor sites. Paclitaxel liposome can be used in cancer-related research.

Para uso exclusivo en investigación. No vendemos a pacientes.

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Paclitaxel liposome Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

IC₅₀ & Target

Estrogen receptor

In Vitro

Anti-cancer

Paclitaxel liposome with different surface modifications enhances cellular internalization or cytotoxicity in KB, BT‑474 and A549 tumor cell lines^[1].
Paclitaxel liposome (15 mol% PTX loading; 72 h) exerts antiproliferative activity against C-26 colon tumor cells (IC₅₀ = 162 nM)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Anti-cancer

Paclitaxel liposome of cation‑modified, PEGylated, hyaluronan‑coated variants realizes tumor‑selective accumulation, raises intratumoral drug concentration and delays metastasis in hamster and Balb/c mouse tumor‑bearing models^[1].
Paclitaxel liposome increases plasma AUC, reduces acute mortality, and inhibits tumor growth in rats, ICR mice, and PC14PE6/AS2 xenograft nude mouse models^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

Appearance Solid
Color White to off-white
SMILES

[Paclitaxel liposome]
Synonyms

Liposomal paclitaxel
Preparation Instructions

This product can only be dissolved and diluted with 5% Dextrose Injection. Do not dissolve or dilute
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Koudelka Š. Liposomal paclitaxel formulations. Journal of Controlled Release, 2012, 163(3):322‑334.

[2]. Kan P, et al. A liposomal formulation able to incorporate a high content of Paclitaxel and exert promising anticancer effect. J Drug Deliv. 2011;2011:629234.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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