Paclitaxel liposome
Based on 1 Customer Validation
Paclitaxel liposome (Liposomal paclitaxel) is a liposome-encapsulated form of Paclitaxel (HY-B0015). Paclitaxel is a natural antitumor agent that stabilizes tubulin polymerization. Paclitaxel liposome exhibits reduced acute toxicity, prolonged circulating half-life of paclitaxel, and enhanced accumulation at tumor sites. Paclitaxel liposome can be used in cancer-related research.
For research use only. We do not sell to patients.
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Estrogen receptor |
Paclitaxel liposome with different surface modifications enhances cellular internalization or cytotoxicity in KB, BT‑474 and A549 tumor cell lines[1].
Paclitaxel liposome (15 mol% PTX loading; 72 h) exerts antiproliferative activity against C-26 colon tumor cells (IC50 = 162 nM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Paclitaxel liposome increases plasma AUC, reduces acute mortality, and inhibits tumor growth in rats, ICR mice, and PC14PE6/AS2 xenograft nude mouse models[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Color White to off-white
-
SMILES
[Paclitaxel liposome]
-
Synonyms
Liposomal paclitaxel
-
Preparation Instructions
This product can only be dissolved and diluted with 5% Dextrose Injection. Do not dissolve or dilute
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)