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  3. Sapienic acid sodium

Sapienic acid sodium 

Cat. No.: HY-130187A Purity: ≥98.0%
COA Handling Instructions

Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.

For research use only. We do not sell to patients.

Sapienic acid sodium Chemical Structure

Sapienic acid sodium Chemical Structure

CAS No. : 217477-25-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in Ethanol USD 121 In-stock
Estimated Time of Arrival: December 31
Oil
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 300 In-stock
Estimated Time of Arrival: December 31
50 mg USD 490 In-stock
Estimated Time of Arrival: December 31
100 mg USD 790 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Sapienic acid sodium:

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  • Biological Activity

  • Purity & Documentation

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Description

Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1].

IC50 & Target

MBC: 31.3 μg/mL (Streptococcus sanguinis), 375.0 μg/mL (Streptococcus mitis) and 93.8 μg/mL (Fusobacterium nucleatum)[1]

In Vitro

Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.39

Formula

C16H29NaO2

CAS No.
SMILES

CCCCCCCCC/C=C\CCCCC(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

Ethanol : 33.33 mg/mL (120.59 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6181 mL 18.0904 mL 36.1808 mL
5 mM 0.7236 mL 3.6181 mL 7.2362 mL
10 mM 0.3618 mL 1.8090 mL 3.6181 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (9.05 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (9.05 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.05 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Sapienic acid sodium
Cat. No.:
HY-130187A
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