Scopolamine-13C,d3 hydrobromide
Scopolamine-13C,d3 (Hyoscine-13C,d3) hydrobromide is the 13C- and deuterium labeled Scopolamine hydrobromide (HY-N0296A). Scopolamine (Hyoscine) hydrobromide is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide can induce cognitive and memory deficits in animals. Scopolamine hydrobromide can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc.
For research use only. We do not sell to patients.
- Formula: C1613CH19D3BrNO4
- Molecular Weight:388.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 114-49-8
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Molecular Weight 388.28
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Formula C1613CH19D3BrNO4
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SMILES
O=C(O[C@H]1C[C@H]2[C@@H]3O[C@@H]3[C@H](N2[13C]([2H])([2H])[2H])C1)[C@@H](C4=CC=CC=C4)CO.Br
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Synonyms
Hyoscine-13C,d3 hydrobromide; Scopine (-)tropate-13C,d3 hydrobromide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)