1 Result for "

1142222-28-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1142222-28-3" in MCE Product Catalog:

Cat. No.: HY-120493
CAS No.: 1142222-28-3
Research Areas:  

Metabolic Disease

(rel)-AM-6226 is the relative stereoisomer of AM-6226 (HY-120493A). AM-6226 is a potent, orally active full agonist of G protein-coupled receptor 40 (GPR40) with an EC50 value of 0.12 μM. AM-6226 activates GPR40 receptors on pancreatic β-cells and enteroendocrine L-cells, promotes insulin secretion in a glucose-dependent manner, and increases the release of incretin hormones (GLP-1, GIP), thus avoiding the risk of hypoglycemia. AM-6226 can be used in the research of metabolic diseases such as diabetes .
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