1 Result for "

1629265-17-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1629265-17-3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-18604
CAS No.: 1629265-17-3
Target:  

Ras

Research Areas:  

Cancer

K-Ras G12C-IN-1 is an irreversible covalent KRAS G12C inhibitor. K-Ras G12C-IN-1 contains an electrophilic group that forms an irreversible covalent bond with Cys12 of mutant K-Ras. After covalent binding to Cys12, it locks Switch II in an inactive state and interferes with downstream Ras signaling. K-Ras G12C-IN-1 can be used in research related to pancreatic cancer, colon cancer, MYH-associated polyposis, colorectal cancer, and lung cancer .
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