1 Result for "

2914919-85-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2914919-85-8" in MCE Product Catalog:

Cat. No.: HY-160023
CAS No.: 2914919-85-8
Synonyms: D3S-001
Target:  

Ras PERK

Research Areas:  

Cancer

Elisrasib (D3S-001) is an orally active and selective inhibitor for KRAS. Elisrasib inhibits the proliferation of KRAS G12C mutant H358 and MIA-PA-CA-2. D3S-001 also inhibits the phosphorylation of cellular ERK1/2. Elisrasib exhibits good metabolic stability in hepatocytes, liver microsomes, plasma and whole blood in various species. D3S-001 exhibits good pharmacokinetic characteristics and antitumor efficacy in mice .
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