1 Result for "

2984506-77-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2984506-77-4" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-148813
CAS No.: 2984506-77-4
Purity:  99.73%
Target:  

PROTACs STAT

Research Areas:  

Cancer

AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models . AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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