1 Result for "

3033583-54-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3033583-54-6" in MCE Product Catalog:

Cat. No.: HY-161176
CAS No.: 3033583-54-6
Target:  

PROTACs Ras ERK

Research Areas:  

Cancer

PROTAC KRAS G12D degrader 1 is a selective PROTAC KRAS G12D degrader. PROTAC KRAS G12D degrader 1 inhibits proliferation of KRAS G12D-mutant cells and suppresses ERK phosphorylation. PROTAC KRAS G12D degrader 1 inhibits tumor growth in mice bearing AsPC-1 xenografts. PROTAC KRAS G12D degrader 1 can be used for the study of KRAS G12D-driven cancers.(Pink: KRAS ligand (HY-175892), Blue: VHL Ligand (HY-112078), Black: Linker, E3 ligase ligand-linker conjugate (HY-175893)) .
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