1 Result for "

3077970-78-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3077970-78-3" in MCE Product Catalog:

Cat. No.: HY-181578
CAS No.: 3077970-78-3
Target:  

NAMPT Apoptosis

Research Areas:  

Cancer

Nampt-IN-17 is an selective orally active NAMPT inhibitor with a human NAMPT IC50 of 17 nM and Ki of 25.9 nM. Nampt-IN-17 depletes intracellular NAD + and ATP, disrupts mitochondrial membrane potential, suppresses cell proliferation, self-renewal, invasion, and migration, induces cell-cycle arrest and apoptosis. Nampt-IN-17 exhibits selective activity against NAPRT-deficient gastric cancer cells. Nampt-IN-17 can be used for the research of NAPRT-deficient gastric cancer .
loading...
    loading...