1 Result for "

441060-02-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "441060-02-2" in MCE Product Catalog:

Cat. No.: HY-182645
CAS No.: 441060-02-2
Target:  

CRFR

Research Areas:  

Neurological Disease

CRF1 receptor antagonist-2 is an orally active, blood-brain barrier permeable CRF1 receptor antagonist, with an IC50 of 4 nM in CHO-K1 cell membranes and an IC50 of 7 nM in rat brain cell membranes. CRF1 receptor antagonist-2 exerts anxiolytic effects in swim stress-loaded rats. CRF1 receptor antagonist-2 can be used in studies related to stress-induced anxiety .
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