4 Results for "

474645-27-7

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "474645-27-7" in MCE Product Catalog:

61
61 Cited Publications
Cat. No.: HY-15162
CAS No.: 474645-27-7
Purity:  99.97%
Synonyms: MMAE; SGD-1010
Research Areas:  

Cancer

Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
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Cat. No.: HY-15162R
CAS No.: 474645-27-7
Synonyms: MMAE (Standard); SGD-1010 (Standard); Vedotin (Standard)
Research Areas:  

Cancer

Monomethyl auristatin E (MMAE) (Standard) is the analytical standard of Monomethyl auristatin E (HY-15162). This product is intended for research and analytical applications. Monomethyl auristatin E is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) against several different cancer types .
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Cat. No.: HY-15162G
CAS No.: 474645-27-7
Synonyms: MMAE (GMP); SGD-1010 (GMP); Vedotin (GMP)
Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor .
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10
10 Cited Publications
Cat. No.: HY-15162A
CAS No.: 2070009-72-0
Purity:  99.15%
Synonyms: Monomethyl auristatin E-d8; Deuterated labeled MMAE
MMAE-d8 is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.
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