3 Results for "

5536-17-4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "5536-17-4" in MCE Product Catalog:

8
Vidarabine
Vidarabine
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8 Cited Publications
Cat. No.: HY-B0277
CAS No.: 5536-17-4
Synonyms: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
Category:  

Infection Microorganisms Antibiotics Antiviral Disease Research Antibacterial Disease Research Fields

Target:  

Nucleoside Antimetabolite/Analog DNA/RNA Synthesis HSV VZV CMV EBV

Vidarabine (Ara-A) is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
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Vidarabine (Standard)
Vidarabine (Standard)
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Cat. No.: HY-B0277R
CAS No.: 5536-17-4
Synonyms: Ara-A (Standard); Adenine Arabinoside (Standard); 9-β-D-Arabinofuranosyladenine (Standard)
Category:  

Microorganisms Antibiotics Antiviral Disease Research Antibacterial

Target:  

Reference Standards Nucleoside Antimetabolite/Analog DNA/RNA Synthesis HSV VZV CMV EBV

Vidarabine (Standard) (Ara-A (Standard)) is the analytical standard of Vidarabine (HY-B0277). This product is intended for research and analytical applications. Vidarabine (Ara-A) is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
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8
Vidarabine monohydrate
Vidarabine monohydrate
0 Images
8 Cited Publications
Cat. No.: HY-N6666
CAS No.: 24356-66-9
Target:  

Nucleoside Antimetabolite/Analog DNA/RNA Synthesis HSV VZV CMV EBV

Research Areas:  

Infection

Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
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