9 Results for "

AcrAB-TolC

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "AcrAB-TolC" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P1649
CAS No.: 1179330-52-9
Synonyms: NAB741
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 .
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3
3 Cited Publications
Cat. No.: HY-P1649B
Synonyms: NAB741 acetate
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate .
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Cat. No.: HY-124819
CAS No.: 957471-96-4
Target:  

Bacterial

Research Areas:  

Infection

D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively . D13-9001 exhibits antibiotic activities .
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Cat. No.: HY-119172
CAS No.: 70-09-7
Purity:  99.84%
Target:  

Bacterial

NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent .
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Cat. No.: HY-155048
CAS No.: 2892824-11-0
Purity:  99.80%
Target:  

Bacterial

Research Areas:  

Infection

BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance .
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Cat. No.: HY-101444
CAS No.: 115871-02-8
Target:  

Bacterial

Research Areas:  

Infection

MC-207110 is a broad-spectrum efflux pump inhibitor. MC-207110 is active against all three known Mex efflux pumps from P. aeruginosa and their close Escherichia coli efflux pump homolog (AcrAB-TolC). MC-207110 can decrease the intrinsic resistance of P. aeruginosa to fluoroquinolones. MC-207110 can be used for the research of infection .
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Cat. No.: HY-119172R
CAS No.: 70-09-7
Target:  

Bacterial

NSC-60339 (Standard) is the analytical standard of NSC-60339. This product is intended for research and analytical applications. NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent .
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Cat. No.: HY-P1649A
Synonyms: NAB741 TFA
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA .
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Cat. No.: HY-183702
CAS No.: 2892824-73-4
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

BDM91531 is a AcrB inhibitor with an EC50 of 0.16 μM against E. coli. BDM91531 acts as an antibiotic potentiator to restore the sensitivity of wild-type Escherichia coli to multiple AcrB substrate antibiotics. BDM91531 exhibits antibacterial activity. BDM91531 can be used in the research of bacterial infections .
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