9 Results for "

AuNPs

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "AuNPs" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-W011500
CAS No.: 51805-45-9
Synonyms: Tris(2-​carboxyethyl)​phosphine hydrochloride
Target:  

Drug Derivative

Research Areas:  

Others

TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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3
3 Cited Publications
Cat. No.: HY-P1812
CAS No.: 1353563-85-5
Synonyms: NP-12
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs) .
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3
3 Cited Publications
Cat. No.: HY-P1812A
Synonyms: NP-12 TFA
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

AUNP-12 TFA (NP-12 TFA) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 TFA exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs) .
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1
1 Cited Publications
Cat. No.: HY-W011500S
CAS No.: 1174025-33-2
TCEP-d16 (hydrochloride) is the deuterium labeled TCEP hydrochloride . TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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Cat. No.: HY-P11347
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

NOTA-AUNP-12 is a PD-L1 antagonist (IC50=2.24×10 −7 M). NOTA-AUNP-12 is promising for research of cancers (e.g., lung/esophageal cancers) .
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Apt-M13 aptamer sodium
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5'-CGGGGGACGTTGCCAACGGTAACGTCGTTGGAT-3', sodium salt
Cat. No.: HY-160044
Apt-M13 aptamer sodium is a mutant 33 nt aptamer based on the original aptamer for dexamethasone (HY-14648). Apt-M13 aptamer sodium can be combined with other nanomaterials for rapid detection of dexamethasone (HY-14648) .
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Cat. No.: HY-130407
CAS No.: 1342764-64-0
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform .
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Cat. No.: HY-W700621
CAS No.: 1189959-10-1
Synonyms: Tris(2-​carboxyethyl)​phosphine hydrochloride-d12
TCEP-d12 (hydrochloride) (Tris(2-?carboxyethyl)?phosphine hydrochloride-d12) is deuterium labeled TCEP (hydrochloride). TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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Cat. No.: HY-W1061685
Research Areas:  

Others

Dithiol Serinol Phosphoramidite is a phosphoramidite reagent for dithiol modification of oligonucleotides. Dithiol Serinol Phosphoramidite contains a serinol linker arm, which keeps the dithiol groups away from the phosphate backbone and allows the sequential introduction of multiple Dithiol Serinol units without the need for additional spacer arm phosphoramidites. Dithiol Serinol Phosphoramidite can be incorporated into oligonucleotides via standard oligonucleotide synthesis and deprotection procedures, and can be introduced sequentially multiple times without adding intermediate spacer arms. Dithiol Serinol Phosphoramidite can be used to prepare multi-dithiol modified oligonucleotides and for surface functionalization studies of gold nanoparticles (AuNPs) .
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