Search Result

Results for "

B ring

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (1) AMPK (1) Apoptosis (2) Aurora Kinase (1) Autophagy (2) Bacterial (3) Biochemical Assay Reagents (5) BMI1 (2) Bradykinin Receptor (1) CaMK (2) Cholinesterase (ChE) (1) Drug Intermediate (3) E1/E2/E3 Enzyme (5) Elastase (1) Endogenous Metabolite (5) Epoxide Hydrolase (2) Fungal (1) Histone Methyltransferase (1) HIV (1) Isotope-Labeled Compounds (4) Ligands for Target Protein for PROTAC (1) Monoamine Oxidase (1) NADPH Oxidase (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (3) PROTACs (2) Reference Standards (2) ROCK (2) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (14) Cardiovascular Disease (3) Endocrinology (2) Infection (5) Inflammation/Immunology (7) Metabolic Disease (4) Neurological Disease (1)

By Targets:

Adrenergic Receptor (1)

Akt (1)

AMPK (1)

Apoptosis (2)

Aurora Kinase (1)

Autophagy (2)

Bacterial (3)

Biochemical Assay Reagents (5)

BMI1 (2)

Bradykinin Receptor (1)

CaMK (2)

Cholinesterase (ChE) (1)

Drug Intermediate (3)

E1/E2/E3 Enzyme (5)

Elastase (1)

Endogenous Metabolite (5)

Epoxide Hydrolase (2)

Fungal (1)

Histone Methyltransferase (1)

HIV (1)

Isotope-Labeled Compounds (4)

Ligands for Target Protein for PROTAC (1)

Monoamine Oxidase (1)

NADPH Oxidase (1)

NO Synthase (1)

Nucleoside Antimetabolite/Analog (3)

PROTACs (2)

Reference Standards (2)

ROCK (2)

Transmembrane Glycoprotein (1)

By Research Areas:

Cancer (14)

Cardiovascular Disease (3)

Endocrinology (2)

Infection (5)

Inflammation/Immunology (7)

Metabolic Disease (4)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-139514

RB-3	E1/E2/E3 Enzyme	Cancer
RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to *RING1B-BMI1f, with a K_d* of 2.8 μM .

HY-108518

SB-772077B dihydrochloride	ROCK	Cardiovascular Disease Inflammation/Immunology
SB-772077B dihydrochloride is an orally active aminofuran-based Rho kinase ((ROCK)) inhibitor with IC₅₀ values of 5.6 nM and 6 nM for ROCK1 and ROCK2, respectively. SB-772077B dihydrochloride reduces inflammatory cytokines (TNF-α and IL-6). SB-772077B dihydrochloride relaxes aortic rings and lowers blood pressure. SB-772077B dihydrochloride can be used in the research of inflammatory diseases .

HY-170823

PRC1-IN-1	E1/E2/E3 Enzyme	Cancer
PRC1-IN-1 is a PRC1 complex inhibitor. PRC1-IN-1 binds to both *RING1A* and *RING1B* proteins, and inhibits the activities of RING1B-BMI1 and RING1B-PCGF1. PRC1-IN-1 effectively inhibits H2AK119 ubiquitination and induces cell differentiation in leukemia cells. PRC1-IN-1 can be used for the research of leukemia .

HY-160924

MS147	PROTACs BMI1 E1/E2/E3 Enzyme Histone Methyltransferase	Cancer
MS147 is a VHL-based PROTAC degrader of BMI1 and RING1B (polycomb repressive complex 1 core components). MS147 directly binds EED and VHL E3 ligase, recruiting the ligase to the EED-BMI1/RING1B complex to induce time-dependent, ubiquitination-mediated degradation of BMI1 and RING1B. MS147 reduces histone H₂A Lys119 mono-ubiquitination without altering histone H₃ Lys27 tri-methylation and inhibits cancer cells proliferation. MS147 can be used for the research of cancer, such as chronic myelogenous leukemia and b-cell lymphoma . (Pink: BMI1/RING1B ligand (HY-183634); Blue: VHL ligand (HY-125845); Black: linker)

HY-34643

6-Heptynoic acid Hept-6-ynoic acid	Drug Intermediate	Others
Hexanoylic acid (Hex-6-ynoic acid) is a drug intermediate. Hexanoylic acid can be functionalized by esterification reaction to paclitaxel (HY-B0015), enabling it to undergo an efficient ring addition reaction with β-cyclodextrin, thereby enhancing its water solubility, stability and targeting properties .

HY-B1449S10

Uridine-13C5 1 Publications Verification β-Uridine-¹³C₅	Isotope-Labeled Compounds	Cancer
Uridine- ¹³C₅ (β-Uridine- ¹³C₅) is a ¹³C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

HY-N0805A

Alisol B 1 Publications Verification	Epoxide Hydrolase CaMK Autophagy Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a K_i of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G₁ phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer .

HY-Y0047

3-Picolylamine Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine	Biochemical Assay Reagents	Inflammation/Immunology
3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .

HY-B1449S11

Uridine-13C9 β-Uridine-¹³C₉	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog	Cancer
Uridine- ¹³C₉ (β-Uridine- ¹³C₉) is a ¹³C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-158239

MS181	PROTACs E1/E2/E3 Enzyme	Cancer
MS181 (compound 1) is a potent cereblon (CRBN)-recruiting and EED-binding polycomb repressive complex 1 (PRC1) PROTAC degrader. MS181 decreases the expression of EED, EZH2, SUZ12, BMI1 and RING1B. MS181 shows antiproliferative activity (Strtucture Note: Red, EED binder (HY-158771); Blue, CRBN ligand (HY-41547); Black, Linker HY-131717) .

HY-103291

Sar-[D-Phe8]-des-Arg9-Bradykinin	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

HY-W751165

Uridine-13C9,15N2 β-Uridine-¹³C₉,¹⁵N₂	Endogenous Metabolite Nucleoside Antimetabolite/Analog Isotope-Labeled Compounds	Cancer
Uridine-13C9,15N2 (β-Uridine-13C9,15N2) is ¹³C and ¹⁵N labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-N3426

Kazinol B	NO Synthase Akt AMPK	Metabolic Disease
Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research .

HY-155477

Cbl-b-IN-15	E1/E2/E3 Enzyme	Cancer
Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ligase Cbl (IC₅₀: 15 nM). *Cbl-b* refers to Casitas B-lineage lymphoma proto-oncogene-b, which inhibits T-cell, natural killer (NK) cell, and B-cell activation. Cbl-b-IN-15 activates T cell function with EC₅₀=0.41 μM .

HY-110225

*Levetiracetam-d6 (ring-d6)* UCB L059-d6 (ring-d6)	Others	Others
Levetiracetam-d6 (ring-d6) can be used as internal standard for the determination of Levetiracetam (HY-B0106) content in whole blood .

HY-W747907

4-Pyridoxolactone β-Pyracin	Endogenous Metabolite	Others
4-Pyridoxolactone (β-Pyracin) is a critical substrate in vitamin B6 degradation pathway I, primarily involved in the vitamin B6 metabolic process mediated by soil microorganisms. 4-Pyridoxolactone serves as the specific substrate for 4-pyridoxolactonase, undergoing a zinc-dependent lactone-ring hydrolysis reaction catalyzed by this enzyme to generate 4-pyridoxic acid (4PA) .

HY-116865

Equilenin	Endogenous Metabolite	Endocrinology Cancer
Equilenin is a B-ring unsaturated estrogen and one of the main ingredients in Premarin, a drug commonly used in estrogen replacement therapy. Equilenin can bind to estrogen receptors in the body and exert effects similar to endogenous estrogen. Equilenin can be used in estrogen replacement therapy and breast cancer research .

HY-B1449S12

Uridine-d12 β-Uridine-d₁₂	Endogenous Metabolite Nucleoside Antimetabolite/Analog Isotope-Labeled Compounds	Cancer
Uridine-d12 (β-Uridine-d12) is the deuterium labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-155902C

Mal-PEG3400-OH Maleimide-PEG3400-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-N14730

De-N-methylpamamycin-593B	Fungal	Infection
De-N-methylpamamycin-593B is a 16-membered ring macrocyclic dilactone. De-N-methylpamamycin-593B has Aerial Mycelium-inducing activity .

HY-142467

HIV-1 inhibitor-11	HIV	Infection
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor. WO2021104413A1 ( compound 1-1b) .

HY-N2641

Dihydrotamarixetin 4'-O-Methyldihydroquercetin; Blumeatin A	NADPH Oxidase	Others
Dihydrotamarixetin (4'-O-Methyldihydroquercetin; Blumeatin A) is a flavonoid with a saturated 2,3-bond and a non-catechol B ring. Dihydrotamarixetin acts as an inhibitor of NADPH Oxidase .

HY-121998

Binucleine 2	Aurora Kinase	Others
Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki=0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division when used at a concentration of 40 μM but does not affect ring ingression, suggesting that Aurora B kinase activity is not required for that step.

HY-162606

MAO-A/B-IN-3	Monoamine Oxidase Cholinesterase (ChE)	Neurological Disease
MAO-A/B-IN-3 (Compound 12) stands out as a key dual MAO-AChE inhibitor, displaying excellent multi-target efficacy against MAO-A, *MAO-B, and AChE* with IC₅₀ values of 67 nM, 29 nM, and 1370 nM respectively. MAO-A/B-IN-3 is adept at altering the A site (hydrophobic ring) and C site (semicarbazone chain) within ketone amine-based MTDLs to bolster the inhibitory potential against *MAO-A/B* while notably diminishing activity against AChE. MAO-A/B-IN-3 is poised for research applications in the field of neurodegenerative diseases .

HY-124178

(R)-Levrazoxane (R)-ICRF 186	Drug Intermediate	Metabolic Disease
(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases .

HY-N0805AR

Alisol B (Standard)	Reference Standards Epoxide Hydrolase CaMK Autophagy Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a K_i of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.

HY-146595

FtsZ-IN-1	Bacterial	Infection
FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity .

HY-155902D

Mal-PEG10000-OH Maleimide-PEG10000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG10000-OH (Maleimide-PEG10000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG10000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-161836

α2AR agonist 1	Adrenergic Receptor	Cardiovascular Disease
α2AR agonist 1 (compound S6a), a new morpholine-containing pyrimidinone, acts as an agonist of α2-adrenoceptor. α2AR agonist 1 induces a concentration-dependent relaxation on aortic ring pre-contracted with Phenylephrine (HY-B0769; pEC₅₀=6.81). α2AR agonist 1 increases NOx and NO levels in HUVECs .

HY-183634

*BMI1/RING1B ligand-1*	Ligands for Target Protein for PROTAC BMI1	Others
BMI1/RING1B ligand-1 is a *BMI1/RING1B* ligand. BMI1/RING1B ligand-1 can be used to synthesize PROTAC S147 (HY-160924).

HY-135755

δ-Lactone	Drug Intermediate	Others
δ-Lactone, an A-ring degradation product, is also an important intermediate in the synthesis of Estrone (HY-B0234), Estradiol (HY-B0141), and their derivatives .

HY-P10814

MciZ (B. subtilis)	Bacterial	Infection
MciZ (B. subtilis), a 40-amino-acid peptide, inhibits the GTPase activity of FtsZ that prevents inappropriate Z-ring formation during sporulation .

HY-N13016

Yinyanghuo C	Transmembrane Glycoprotein	Cancer
Yinyanghuo C is a prenylated flavonoid isolated from the leaves of Epimedium sagittatum. Yinyanghuo C increases the mRNA expression levels of endothelial cell markers and enhances cancer-associated angiogenesis in the 4T1 breast tumor-bearing model .

HY-108518R

SB-772077B dihydrochloride (Standard)	Reference Standards ROCK	Cardiovascular Disease Inflammation/Immunology
SB-772077B dihydrochloride (Standard) is the analytical standard of SB-772077B (dihydrochloride) (HY-108518). This product is intended for research and analytical applications. SB-772077B dihydrochloride is an orally active aminofuran-based Rho K_inase ((ROCK)) inhibitor with IC₅₀ values of 5.6 nM and 6 nM for ROCK1 and ROCK2, respectively. SB-772077B dihydrochloride reduces inflammatory cytoK_ines (TNF-α and IL-6). SB-772077B dihydrochloride relaxes aortic rings and lowers blood pressure. SB-772077B dihydrochloride can be used in the research of inflammatory diseases .

HY-N19662

12-Methoxy-cis-carnosic acid	Bacterial	Infection
12-Methoxy-cis-carnosic acid (Compound 5) is a methoxylated aromatic abietane diterpene with a cis A/B ring junction, found in the aerial parts of Rosmarinus officinalis. 12-Methoxy-cis-carnosic acid can be used for research on Methicillin (HY-121544)-resistant Staphylococcus aureus .

HY-N19297

Endosidin1 Prieurianin	Elastase	Inflammation/Immunology Cancer
Endosidin1 (Prieurianin) is a Prieurianin with cleaved A and B rings. Endosidin1 is isolated from the roots of Aphanamixis polystachya. Endosidin1 inhibits superoxide anion production and Elastase release in neutrophils, with an IC₅₀ >10 μg/mL. Endosidin1 exhibits mild cytotoxic activity against laryngeal cancer cells in vitro. Endosidin1 shows anti-inflammatory activity. Endosidin1 can be used in studies related to laryngeal cancer .\n

HY-155902H

Mal-PEG40000-OH Maleimide-PEG40000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG40000-OH (Maleimide-PEG40000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG40000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-155902E

Mal-PEG20000-OH Maleimide-PEG20000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG20000-OH (Maleimide-PEG20000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG20000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

Cat. No.	Product Name

HY-L068

Flavonoids Library	576 compounds
Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc. MCE offers a unique collection of 576 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

Flavonoids Library

576 compounds

Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc.

MCE offers a unique collection of 576 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

HY-L928

GPCR Targeted Diversity Library	7,115 compounds
G protein-coupled receptors (GPCRs) are membrane proteins in humans and one of the most important targets in drug discovery. Approximately 35% of launched drugs are targeted GPCRs, making them a crucial class of targets in drug discovery. The orthosteric site of a GPCR is its endogenous ligand’s (such as neurotransmitters or hormones) binding site. This site plays a central role in signal transduction. Small molecules binding to this site typically contain a protonatable amino group, enabling the formation of salt bridges or hydrogen bonds with acidic residues in the binding pocket. In contrast, the allosteric site does not directly initiate signaling but modulates the signal intensity of the GPCR by altering or stabilizing the conformation of the orthosteric site. Small molecules binding to the allosteric site often contain multiple aromatic rings to occupy hydrophobic pockets and achieve their functional effects. MCE has collected over 7,115 reported bioactive molecules targeting GPCRs, covering Class A, B, and C GPCRs. These small molecules were subjected to AI representation to extract 2D and 3D features. Subsequently, we do screening by AI score based on similarity to identify molecules in diversity library highly similar to the reported bioactive molecules in both 2D and 3D, with a threshold greater than 0.7. Further screening based on cLogP was applied to select molecules with good lipophilicity, which facilitates the binding of small molecules to GPCRs. This diversity library can be widely applied to the discovery of compounds targeting GPCR proteins.

GPCR Targeted Diversity Library

7,115 compounds

G protein-coupled receptors (GPCRs) are membrane proteins in humans and one of the most important targets in drug discovery. Approximately 35% of launched drugs are targeted GPCRs, making them a crucial class of targets in drug discovery.

The orthosteric site of a GPCR is its endogenous ligand’s (such as neurotransmitters or hormones) binding site. This site plays a central role in signal transduction. Small molecules binding to this site typically contain a protonatable amino group, enabling the formation of salt bridges or hydrogen bonds with acidic residues in the binding pocket. In contrast, the allosteric site does not directly initiate signaling but modulates the signal intensity of the GPCR by altering or stabilizing the conformation of the orthosteric site. Small molecules binding to the allosteric site often contain multiple aromatic rings to occupy hydrophobic pockets and achieve their functional effects.

MCE has collected over 7,115 reported bioactive molecules targeting GPCRs, covering Class A, B, and C GPCRs. These small molecules were subjected to AI representation to extract 2D and 3D features. Subsequently, we do screening by AI score based on similarity to identify molecules in diversity library highly similar to the reported bioactive molecules in both 2D and 3D, with a threshold greater than 0.7. Further screening based on cLogP was applied to select molecules with good lipophilicity, which facilitates the binding of small molecules to GPCRs. This diversity library can be widely applied to the discovery of compounds targeting GPCR proteins.

Cat. No.	Product Name	Type

HY-155902C

Mal-PEG3400-OH Maleimide-PEG3400-Hydroxy	Biochemical Assay Reagents
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-155902D

Mal-PEG10000-OH Maleimide-PEG10000-Hydroxy	Biochemical Assay Reagents
Mal-PEG10000-OH (Maleimide-PEG10000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG10000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-155902H

Mal-PEG40000-OH Maleimide-PEG40000-Hydroxy	Biochemical Assay Reagents
Mal-PEG40000-OH (Maleimide-PEG40000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG40000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-155902E

Mal-PEG20000-OH Maleimide-PEG20000-Hydroxy	Biochemical Assay Reagents
Mal-PEG20000-OH (Maleimide-PEG20000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG20000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

Cat. No.	Product Name	Target	Research Area

HY-103291

Sar-[D-Phe8]-des-Arg9-Bradykinin	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

HY-P10814

MciZ (B. subtilis)	Bacterial	Infection
MciZ (B. subtilis), a 40-amino-acid peptide, inhibits the GTPase activity of FtsZ that prevents inappropriate Z-ring formation during sporulation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0805A

Alisol B 1 Publications Verification	Triterpenes Structural Classification Alisma plantago-aquatica Linn. Classification of Application Fields Terpenoids Metabolic Disease Alismataceae Plants Disease Research Fields Source Classification	Epoxide Hydrolase CaMK Autophagy Apoptosis
Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a K_i of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G₁ phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer .

HY-N3426

Kazinol B	other families Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	NO Synthase Akt AMPK
Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research .

HY-W747907

4-Pyridoxolactone β-Pyracin	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
4-Pyridoxolactone (β-Pyracin) is a critical substrate in vitamin B6 degradation pathway I, primarily involved in the vitamin B6 metabolic process mediated by soil microorganisms. 4-Pyridoxolactone serves as the specific substrate for 4-pyridoxolactonase, undergoing a zinc-dependent lactone-ring hydrolysis reaction catalyzed by this enzyme to generate 4-pyridoxic acid (4PA) .

HY-N14730

De-N-methylpamamycin-593B	Natural Products Microorganisms Source Classification	Fungal
De-N-methylpamamycin-593B is a 16-membered ring macrocyclic dilactone. De-N-methylpamamycin-593B has Aerial Mycelium-inducing activity .

HY-N2641

Dihydrotamarixetin 4'-O-Methyldihydroquercetin; Blumeatin A	Structural Classification Flavanonols Flavonoids Plants Compositae Stuhlmannia moavi Taub. Source Classification	NADPH Oxidase
Dihydrotamarixetin (4'-O-Methyldihydroquercetin; Blumeatin A) is a flavonoid with a saturated 2,3-bond and a non-catechol B ring. Dihydrotamarixetin acts as an inhibitor of NADPH Oxidase .

HY-N0805AR

Alisol B (Standard)	Triterpenes Structural Classification Alisma plantago-aquatica Linn. Terpenoids Alismataceae Plants Source Classification	Reference Standards Epoxide Hydrolase CaMK Autophagy Apoptosis
Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a K_i of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.

HY-N13016

Yinyanghuo C	Structural Classification Flavonoids Epimedium sagittatum (Siebold & Zucc.) Maxim. Plants Berberidaceae Other Flavonoids Source Classification	Transmembrane Glycoprotein
Yinyanghuo C is a prenylated flavonoid isolated from the leaves of Epimedium sagittatum. Yinyanghuo C increases the mRNA expression levels of endothelial cell markers and enhances cancer-associated angiogenesis in the 4T1 breast tumor-bearing model .

HY-N19662

12-Methoxy-cis-carnosic acid	Structural Classification Paramacrolobium coeruleum (Taub.) J.Léonard Ketones, Aldehydes, Acids Labiatae Plants Source Classification	Bacterial
12-Methoxy-cis-carnosic acid (Compound 5) is a methoxylated aromatic abietane diterpene with a cis A/B ring junction, found in the aerial parts of Rosmarinus officinalis. 12-Methoxy-cis-carnosic acid can be used for research on Methicillin (HY-121544)-resistant Staphylococcus aureus .

HY-N19297

Endosidin1 Prieurianin	Structural Classification Natural Products Arabidopsis thaliana (L.) Heynh. Plants Brassicaceae Source Classification	Elastase
Endosidin1 (Prieurianin) is a Prieurianin with cleaved A and B rings. Endosidin1 is isolated from the roots of Aphanamixis polystachya. Endosidin1 inhibits superoxide anion production and Elastase release in neutrophils, with an IC₅₀ >10 μg/mL. Endosidin1 exhibits mild cytotoxic activity against laryngeal cancer cells in vitro. Endosidin1 shows anti-inflammatory activity. Endosidin1 can be used in studies related to laryngeal cancer .\n

Species:	Human (14) Mouse (2)
Tag:	His (12) Tag Free (4) Avi (8) B2M (1)
Source:	HEK293 (8) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701546

	RNF113B Protein, Human RNF113B; ring finger protein 113B; Zinc finger protein 183-like 1	Human	E. coli
	The RING finger (RNF) protein contains the RING domain, and exerts E3 ubiquitin ligase that mediates the covalent attachment of ubiquitin to target proteins. RNF113B belongs to the RNF protein family. RNF113B Protein, Human is the recombinant human-derived RNF113B protein, expressed by E. coli , with tag free.

HY-P701547

	RNF113B Protein, Human (His) RNF113B; ring finger protein 113B; Zinc finger protein 183-like 1	Human	E. coli
	The RING finger (RNF) protein contains the RING domain, and exerts E3 ubiquitin ligase that mediates the covalent attachment of ubiquitin to target proteins. RNF113B belongs to the RNF protein family. RNF113B Protein, Human (His) is the recombinant human-derived RNF113B protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701562

	RNF216 Protein, Human RNF216; E3 ubiquitin-protein ligase RNF216; ring finger protein 216; ring-type E3 ubiquitin transferase RNF216; Triad domain-containing protein 3; Ubiquitin-conjugating enzyme 7-interacting protein 1; Zinc finger protein inhibiting NF-kappa-B	Human	E. coli
	The RNF216 protein accepts ubiquitin from specific enzymes and transfers it to the substrate, promoting its ubiquitination. It has antiviral activity, inhibits TNF- and IL-1-mediated NF-kappa-B activation, and promotes TNF- and RIP-mediated apoptosis. RNF216 Protein, Human is the recombinant human-derived RNF216 protein, expressed by E. coli , with tag free.

HY-P701563

	RNF216 Protein, Human (His) RNF216; E3 ubiquitin-protein ligase RNF216; ring finger protein 216; ring-type E3 ubiquitin transferase RNF216; Triad domain-containing protein 3; Ubiquitin-conjugating enzyme 7-interacting protein 1; Zinc finger protein inhibiting NF-kappa-B	Human	E. coli
	The RNF216 protein accepts ubiquitin from specific enzymes and transfers it to the substrate, promoting its ubiquitination. It has antiviral activity, inhibits TNF- and IL-1-mediated NF-kappa-B activation, and promotes TNF- and RIP-mediated apoptosis. RNF216 Protein, Human (His) is the recombinant human-derived RNF216 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P77766

	*HLA-A02:01&B2M&LMP2(CLGGLLTMV) Monomer Protein, Human (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P77768

	*HLA-A02:01&B2M&LMP2(CLGGLLTMV) Tetramer Protein, Human (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P700933

	*HLA-A11:01&B2M&LMP2(SSCSSCPLTK) Monomer Protein, Human (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P700934

	*HLA-A11:01&B2M&LMP2(SSCSSCPLTK) Tetramer Protein, Human (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P77767

	*HLA-A02:01&B2M&LMP2(CLGGLLTMV) Monomer Protein, Human (Biotinylated, HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P700932

	*HLA-A11:01&B2M&LMP2(SSCSSCPLTK) Monomer Protein, Human (Biotinylated, HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Human	HEK293

HY-P702072

	DTX3L Protein, Human DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BAL-associated protein; Protein deltex-3-like; ring-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human is the recombinant human-derived DTX3L protein, expressed by E. coli , with tag free.

HY-P702076

	RBCK1 Protein, Human RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1; HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; HOIL-1; Hepatitis B virus X-associated protein 4; ring finger protein 54; ring-type E3 ubiquitin transferase HOIL-1; Ubiquitin-conjugating enzyme 7-interacting protein 3	Human	E. coli
	RBCK1 is an E3 ubiquitin protein ligase that cooperates with specific E2 enzymes such as UBE2L3/UBCM4 to transfer ubiquitin to substrates. It acts as an E3 ligase that oxidizes IREB2, relying on heme and oxygen for IREB2 ubiquitination. RBCK1 Protein, Human is the recombinant human-derived RBCK1 protein, expressed by E. coli , with tag free.

HY-P77772

	*Chimeric HLA-A02:01(mα3)&B2M&LMP2(CLGGLLTMV) Tetramer Protein, Human&Mouse (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Mouse	HEK293

HY-P77771

	*Chimeric HLA-A02:01(mα3)&B2M&LMP2(CLGGLLTMV) Monomer Protein, Human&Mouse (HEK293, His-Avi)** MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; ring12	Mouse	HEK293

HY-P702073

	DTX3L Protein, Human (His) DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BAL-associated protein; Protein deltex-3-like; ring-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human (His) is the recombinant human-derived DTX3L protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71637

	TRIM5 Protein, Human (His, B2M) ring finger protein 88; RNF88; TRIM5; TRIM5_HUMAN; TRIM5alpha; Tripartite motif containing 5; tripartite motif protein TRIM5; Tripartite motif-containing protein 5	Human	E. coli
	The TRIM5 protein is a capsid-specific restriction factor that prevents non-host adapted retroviral infection. TRIM5 acts as a pattern recognition receptor that activates innate immune signaling by triggering E3 ubiquitin ligase activity upon binding to viral capsids. TRIM5 restricts various retroviruses and regulates autophagy. TRIM5 Protein, Human (His, B2M) is the recombinant human-derived TRIM5 protein, expressed by E. coli , with N-His, B2M labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B1449S10

Uridine-13C5 1 Publications Verification
Uridine- ¹³C₅ (β-Uridine- ¹³C₅) is a ¹³C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

HY-B1449S11

Uridine-13C9
Uridine- ¹³C₉ (β-Uridine- ¹³C₉) is a ¹³C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-W751165

Uridine-13C9,15N2
Uridine-13C9,15N2 (β-Uridine-13C9,15N2) is ¹³C and ¹⁵N labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-B1449S12

Uridine-d12
Uridine-d12 (β-Uridine-d12) is the deuterium labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

Host:	Mouse (3) Rabbit (11)
Reactivity:	Human (14) Rat (8) Mouse (7)
Application:	IHC-P (9) ICC/IF (6) IF-Tissue (1) IP (4) IHC-F (2) WB (12) FC (1) Dot Blot (1) ELISA (1)
Isotype:	IgG (11) IgG1 (2)
Conjugation:	Non-conjugated (14) Biotin (2)
Clonality:	Monoclonal (8) Recombinant (5)
Modification:	Phosphorylated (2) Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83585

	RING2 Antibody (YA3330) BAP1; DING; BAP-1; HIPI3; ring2; ring1B	WB, IHC-P	Human
	RING2 Antibody (YA3330) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RING2.

HY-P83585A

	RING2 Antibody (YA3330)(PBS only) BAP1; DING; BAP-1; HIPI3; ring2; ring1B	WB, IHC-P	Human
	RING2 Antibody (YA3330) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RING2.

HY-P88644

	HSD17B8 Antibody (YA8328) D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; ring2; SDR30C1	IHC-P	Human, Mouse, Rat
	HSD17B8 Antibody (YA8328) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B8.

HY-P88644A

	HSD17B8 Antibody (YA8328)(PBS only) D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; ring2; SDR30C1	IHC-P	Human, Mouse, Rat
	HSD17B8 Antibody (YA8328) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B8.

HY-P82647

	CBL Antibody (YA2392) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB, ICC/IF, IP	Human
	CBL Antibody (YA2392) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CBL.

HY-P85077

	Cbl Antibody (YA4769) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat
	Cbl Antibody (YA4769) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cbl.

HY-P82647A

	CBL Antibody (YA2392)(PBS only) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB, ICC/IF, IP	Human
	CBL Antibody (YA2392) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CBL.

HY-P81294

	Phospho-CBL (Tyr774) Antibody (YA1014) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB, IP	Human, Rat
	Phospho-CBL (Tyr774) Antibody (YA1014) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CBL (Tyr774).

HY-P81294A

	Phospho-CBL (Ser669) Antibody (YA1015) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB	Human
	Phospho-CBL (Ser669) Antibody (YA1015) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CBL (Ser669).

HY-P81294AA

	Phospho-CBL (Ser669) Antibody (YA1015)(PBS only) CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; ring finger protein 55; Signal transduction protein CBL	WB	Human
	Phospho-CBL (Ser669) Antibody (YA1015) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CBL (Ser669).

HY-P80730

	KAP1 Antibody (YA3523) TRIM28; KAP1; RNF96; TIF1B; Transcription intermediary factor 1-beta; TIF1-beta; E3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; ring finger protein 96; Tripart	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	KAP1 Antibody (YA3523) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KAP1.

HY-P80730A

	KAP1 Antibody (YA3523)(PBS only) TRIM28; KAP1; RNF96; TIF1B; Transcription intermediary factor 1-beta; TIF1-beta; E3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; ring finger protein 96; Tripart	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	KAP1 Antibody (YA3523) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KAP1.

HY-P810547

	Phospho-KAP1 (Ser824) Antibody (YA9816) TRIM28; KAP1; RNF96; TIF1B; Transcription intermediary factor 1-beta; TIF1-beta; E3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; ring finger protein 96; Tripart	WB, IHC-P, IP, Dot Blot, ICC/IF	Human, Mouse, Rat
	Phospho-KAP1 (Ser824) Antibody (YA9816) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-KAP1 (Ser824).

HY-P85505

	KAP1 Antibody (YA5197) E3 SUMO protein ligase TRIM28; E3 SUMO-protein ligase TRIM28; FLJ29029; KAP 1; KAP-1; KRAB associated protein 1; KRAB interacting protein 1; KRAB-associated protein 1; KRAB-interacting protein 1; KRIP 1; KRIP-1; KRIP1; Nuclear corepressor KAP 1; Nuclear corepressor KAP-1; ring finger protein 96; RNF96; TF1B; TIF1 beta; TIF1-beta; TIF1B; TIF1B_HUMAN; Transcription intermediary factor 1 beta; Transcription intermediary factor 1-beta; TRIM28; Tripartite motif containing 28; tripartite motif containing protein 28; Tripartite motif-containing protein 28.	WB, IHC-P, IF-Tissue	Human, Mouse, Rat
	KAP1 Antibody (YA5197) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to KAP1.