120882-22-6
Chemical Structure
Desfuroylceftiofur
- CAS No.: 120882-22-6
- Formula:C14H15N5O5S3
- Molecular Weight:429.49
IUPAC Name: (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: OITCOWCNESRWSM-GHXIOONMSA-N
SMILES: O=C(C(N12)=C(CS)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O
Biological Activity: Desfuroylceftiofur is an antibacterial agent and the active metabolite of Ceftiofur sodium (HY-B0898) with an intact β-lactam ring. Desfuroylceftiofur exhibits inhibitory activity against Gram-negative and Gram-positive pathogenic bacteria of veterinary interest in vitro. Desfuroylceftiofur can be used in the research of bovine respiratory disease, porcine respiratory disease, equine lymphadenitis, bovine mastitis, turkey colibacillosis, suppurative arthritis and respiratory infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Desfuroylceftiofur | 85.0% | Desfuroylceftiofur is an antibacterial agent and the active metabolite of Ceftiofur sodium (HY-B0898) with an intact β-lactam ring. Desfuroylceftiofur exhibits inhibitory activity against Gram-negative and Gram-positive pathogenic bacteria of veterinary interest in vitro. Desfuroylceftiofur can be used in the research of bovine respiratory disease, porcine respiratory disease, equine lymphadenitis, bovine mastitis, turkey colibacillosis, suppurative arthritis and respiratory infections. | ||||||||||||||||||||
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Desfuroylceftiofur-d3 sodium | Desfuroylceftiofur-d3 sodium is the deuterium labeled Desfuroylceftiofur sodium (HY-126818). Desfuroylceftiofur is a metabolite of Ceftiofur (HY-N7102) and an Antibacterial agent. Desfuroylceftiofur exhibits comparable activity against Gram-negative bacteria to that of Ceftiofur. | |||||||||||||||||||||
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- [1]. Salmon SA, et al. In vitro activity of ceftiofur and its primary metabolite, desfuroylceftiofur, against organisms of veterinary importance. J Vet Diagn Invest. 1996;8(3):332-336. [Content Brief]
- [2]. S De Baere, et al. High-performance liquid chromatographic-UV detection analysis of ceftiofur and its active metabolite desfuroylceftiofur in horse plasma and synovial fluid after regional intravenous perfusion and systemic intravenous injection of ceftiofur sodium. Analytica Chimica Acta. Volume 512, Issue 1, 4 June 2004, Pages 75-84.
