1 Result for "

BTK-eGFP

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "BTK-eGFP" in MCE Product Catalog:

Cat. No.: HY-163295
CAS No.: 2377645-56-0
Target:  

PROTACs Btk ADC Payloads

Research Areas:  

Cancer

PROTAC BTK Degrader-16 is a BTK PROTAC degrader with a DC50 of 0.0006 nM in TMD8 cells. PROTAC BTK Degrader-16 recruits E3 ligase CRBN to tag BTK for degradation, leading to loss of BTK signaling. PROTAC BTK Degrader-16 induces degradation of BTK, leading to inhibition of cell growth in ABC-DLBCL cells. PROTAC BTK Degrader-16 can be used for the research of activated b-cell-like diffuse large b-cell lymphoma (ABC-DLBCL) .
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