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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
CAXII-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "CAXII-IN-1" in MCE Product Catalog:
Cat. No.: HY-143460
CAS No.: 2479918-59-5
Target:
Research Areas:
CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity [1].
Cat. No.: HY-146819
CAS No.: 2439165-37-2
Target:
Research Areas:
Compound 9 is the most effective against tumor specific Ca ix/ca XII (ki=29.1 and 8.8 nm), so it is possible to evaluate its cytotoxicity and selectivity to HepG-2, HCT-116 and MCF-7 cancer cell lines in vitro, and its IC50 values to tumor cells are 1.78, 1.94 and 3.07, respectively μ M. It showed that it had obvious cytotoxicity.
Cat. No.: HY-175239
Target:
Research Areas:
CAII/CAXII-IN-1 (compound 8d) is a CAII/CAXII inhibitor with IC50 values of 0.38 µM and 0.61 µM for CAII and CAXII, respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
