1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase
  3. CAXII-IN-1

CAXII-IN-1 

Cat. No.: HY-143460
Handling Instructions

CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity.

For research use only. We do not sell to patients.

CAXII-IN-1 Chemical Structure

CAXII-IN-1 Chemical Structure

CAS No. : 2479918-59-5

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Description

CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity[1].

IC50 & Target

IC50: 3.8 nM (hCA XII), 56.0 nM (hCA IX)[1]

In Vitro

CAXII-IN-1 (Compound 17) shows cytotoxicity with IC50 values of 20±1, 4.8±0.03 and 14±2 µM against MCF-7, HeLa and A549 cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

328.17

Formula

C13H7Cl2NO3S

CAS No.
SMILES

ClC1=CC(Cl)=CC(C2=CN=C(OS(C=C3)(=O)=O)C3=C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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CAXII-IN-1
Cat. No.:
HY-143460
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