48 Results for "

CD14

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "CD14" in MCE Product Catalog:

5
5 Cited Publications
Referencia número: HY-N9965
No. CAS: 41263-94-9
Synonyms: 2'-FL
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .
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3
3 Cited Publications
Referencia número: HY-135750
No. CAS: 574759-62-9
Pureza:  99.90%
Áreas de investigación:  

Inflammation/Immunology

VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14 +CD11b + monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects .
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2
2 Cited Publications
Referencia número: HY-P99008
No. CAS: 2417175-94-9
Synonyms: IC14
Atibuclimab (IC14), is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab attenuates Lipopolysaccharides (HY-D1056) (LPS)-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. Atibuclimab can be used for the research of amyotrophic lateral sclerosis, sepsis, community-acquired pneumonia, or acute lung injury .
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1
1 Cited Publications
Referencia número: HY-W251428
No. CAS: 383907-64-0
Synonyms: Egg PG
Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV) .
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1
1 Cited Publications
Referencia número: HY-P75444
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Source:  
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Referencia número: HY-W040255
No. CAS: 89947-79-5
Synonyms: PGPC
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is an oxidized phospholipid. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine reduces the viability of HUVECs, increases the levels of ferrous ions and lipid peroxidation, promotes the production of superoxide anions, and decreases the levels of glutathione and GPX4 in cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine upregulates the mRNA and protein levels of FABP3 in HUVECs, impairs mitochondrial membrane potential, and induces ferroptosis-related changes as well as mitochondrial dysfunction and damage. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine activates caspase-11 and promotes the continuous release of IL-1β from macrophages and dendritic cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine inhibits the proliferation of aortic smooth muscle cells and induces apoptosis in these cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is applicable to relevant research on atherosclerosis .
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Referencia número: HY-129684
No. CAS: 1202388-64-4
Áreas de investigación:  

Infection Inflammation/Immunology

IAXO-101 iodide is a TLR4/CD14 blocker. IAXO-101 iodide can inhibit the innate immune pathway of CD14. IAXO-101 iodide is capable of improving the recording performance of intracortical microelectrodes in mice. IAXO-101 iodide can also partially alleviate fetal growth restriction, placental vascular damage, and reduce the level of the inflammatory factor TNF-α in pregnant mice infected with malaria. IAXO-101 iodide can be used in the research of gestational malaria and inflammatory diseases .
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Referencia número: HY-RS02189
Áreas de investigación:  

Others

CD14 Human Pre-designed siRNA Set A contains three designed siRNAs for CD14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-RS23162
Áreas de investigación:  

Others

Cd14 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd14 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-RS16726
Áreas de investigación:  

Others

Cd14 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd14 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P991004
No. CAS: 2923687-56-1
Synonyms: LB-101

Target:  

CD47 PD-1/PD-L1

Áreas de investigación:  

Cancer

Itanistomig (LB-101) is a tetravalent bispecific antibody targeting PD-L1 and CD47. Itanistomig blocks PD-L1 and achieves tumor enrichment through binding to PD-L1, and also exerts conditional CD47 blocking activity via cleavage of the hinge linker in the PD-L1-positive tumor microenvironment. Itanistomig induces antibody-dependent cellular phagocytosis in human CD14 + cells and drives tumor regression. Itanistomig can be used in research related to solid tumors .
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Referencia número: HY-101132A
No. CAS: 873842-97-8
Áreas de investigación:  

Inflammation/Immunology

(Rac)-VB-201 is the racemate of VB-201, an oxidized phospholipid small molecule that inhibits CD14- and toll-like receptor 2-dependent innate cell activation and suppresses atherosclerosis .
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Referencia número: HY-151399
No. CAS: 2978694-04-9
Target:  

Bacterial

Áreas de investigación:  

Infection

Antimicrobial agent-5 is an potent antimicrobial agent, and displays excellent cell selectivity against Gram-negative bacteria and Gram-positive bacteria. Antimicrobial agent-5 blocks the interaction between LPS and CD14/TLR4 receptor, and shows anti-inflammatory activity against LPS-induced inflammation .
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Referencia número: HY-P991845

Áreas de investigación:  

Inflammation/Immunology

Anti-CD14 Antibody (UCHM-1) reacts with the human CD14. Anti-CD14 Antibody (UCHM-1) recognizes a cell surface glycoprotein expressed on most peripheral blood monocytes. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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Referencia número: HY-101132
No. CAS: 630112-41-3
Target:  

Endogenous Metabolite

Áreas de investigación:  

Inflammation/Immunology

VB-201 is an oxidized phospholipid small molecule with anti-inflammatory activity. VB-201 inhibits CD14- and Toll-like receptor 2-dependent innate cell activation. VB-201 limits the progression of atherosclerosis and can be used to study atherosclerosis .
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Referencia número: HY-P74331
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Rat
Source:  
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Referencia número: HY-P75445
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Source:  
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Referencia número: HY-P74332
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Rat
Source:  
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Referencia número: HY-P78918
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Source:  
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Referencia número: HY-P74333
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Monocyte Differentiation Antigen CD14; CD14
Species:  
Source:  
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