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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Ceramide synthases
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Ceramide synthases" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-N6719
CAS No.: 116355-83-0
Category:
Infection Human Gut Microbiota Metabolites Microorganisms Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics
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7
7 Cited Publications
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Genz-123346 free base is an orally available inhibitor of glucosylceramide synthase. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 of 14 nM .
7
7 Cited Publications
Cat. No.: HY-12744A
CAS No.: 943344-58-9
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Research Areas:
Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM .
1
1 Cited Publications
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P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator .
Cat. No.: HY-N6723
CAS No.: 116355-84-1
Category:
Infection Human Gut Microbiota Metabolites Microorganisms Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics
Target:
Cat. No.: HY-W356117
CAS No.: 94885-03-7
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Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research .
Cat. No.: HY-D1573
CAS No.: 114301-99-4
Cat. No.: HY-N6730
CAS No.: 145040-09-1
Synonyms: Aminopentol
Category:
Target:
Cat. No.: HY-N6723S
CAS No.: 1217481-36-1
Cat. No.: HY-N6719S
CAS No.: 1217458-62-2
Cat. No.: HY-175198
CAS No.: 2928129-57-9
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Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research .
Cat. No.: HY-133491
CAS No.: 1402702-76-4
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ST1060 is a Ceramide synthase 2 (CerS2) inhibitor. ST1060 reduces the levels of long-chain dihydroceramide (dhCer) produced by CerS2 catalysis, with IC50 values of 63.6 μM and 61.3 μM for C24:0 and C24:1, respectively. ST1060 is applicable to the research of ceramide metabolism disorders and cervical cancer .
Cat. No.: HY-183140
CAS No.: 1629992-28-4
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DH20931 is a ceramide synthase 2 (CerS2) activator. DH20931 inhibits growth of cancer cells by inducing lipotoxic endoplasmic reticulum (ER) stress. DH20931 shows synergistic anti-tumor efficacy with Doxorubicin (HY-15142A). DH20931 can be used for the research of breast cancer .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
