2748196-63-4
Chemical Structure
P053
- CAS No.: 2748196-63-4
- Formula:C18H21Cl2NO2
- Molecular Weight:354.27
IUPAC Name: (S)-2-amino-4-(4-((3,4-dichlorobenzyl)oxy)phenyl)-2-methylbutan-1-ol
InChIKey: ZQQHXJCIFGMUPY-SFHVURJKSA-N
SMILES: OC[C@@](C)(N)CCC1=CC=C(OCC2=CC=C(Cl)C(Cl)=C2)C=C1
Biological Activity: P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator[1].
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P053 | 97.0% | P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator. | ||||||||||||||||||||
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Keywords