(R)-AAL
Customer Review
Based on 1 Customer Validation
(R)-AAL is an immunomodulator. (R)-AAL decreases circulating T lymphocytes in rats, with an ID50 value of 0.009 mg/kg. (R)-AAL is a substrate of sphingosine kinase (SphK), which catalyzes the phosphorylation of (R)-AAL.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 241476-71-1
- Formula: C18H31NO2
- Molecular Weight:293.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Size
Price
Stock
Quantity
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
2.32 μM
Compound: AAL(R)
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Inhibition of wild type human Jurkat cells after 18 hrs by MTT assay
Inhibition of wild type human Jurkat cells after 18 hrs by MTT assay
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[PMID: 17400555] |
| Jurkat | IC50 |
7.12 μM
Compound: AAL(R)
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Inhibition of human 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR3 mutant cells proliferation after 18 hrs by MTT assay
Inhibition of human 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR3 mutant cells proliferation after 18 hrs by MTT assay
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[PMID: 17400555] |
| Jurkat | IC50 |
7.72 μM
Compound: AAL(R)
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Inhibition of 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR2 mutant cells proliferation after 18 hrs by MTT assay
Inhibition of 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR2 mutant cells proliferation after 18 hrs by MTT assay
|
[PMID: 17400555] |
| Jurkat | IC50 |
8.72 μM
Compound: AAL(R)
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Inhibition of 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR1 mutant cells proliferation after 18 hrs by MTT assay
Inhibition of 2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol-resistant human Jurkat SBR1 mutant cells proliferation after 18 hrs by MTT assay
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[PMID: 17400555] |
Chemical Information
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CAS No. 241476-71-1
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Appearance Solid
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Molecular Weight 293.44
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Formula C18H31NO2
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Color White to off-white
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SMILES
OC[C@](C)(N)CCC1=CC=C(C=C1)OCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
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Data Sheet (262 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Molarity Calculator
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Dilution Calculator
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