943344-58-9

Genz-123346 Chemical Structure
943344-58-9

Chemical Structure

Genz-123346

  • CAS No.: 943344-58-9
  • Formula:C24H38N2O4·1/2C4H6O6
  • Molecular Weight:493.63

IUPAC Name: N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)nonanamide hemi((2R,3R)-2,3-dihydroxysuccinate)

InChIKey: ZRGZTIAIHNUMCZ-DQKXIDSGSA-N

SMILES: CCCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O.[1/2]

Biological Activity: Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM[1].

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-12744A
Genz-123346 98.86% Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References