943344-58-9
943344-58-9
Chemical Structure
Genz-123346
- CAS No.: 943344-58-9
- Formula:C24H38N2O4·1/2C4H6O6
- Molecular Weight:493.63
IUPAC Name: N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)nonanamide hemi((2R,3R)-2,3-dihydroxysuccinate)
InChIKey: ZRGZTIAIHNUMCZ-DQKXIDSGSA-N
SMILES: CCCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O.[1/2]
Biological Activity: Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Genz-123346 | 98.86% | Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM. | ||||||||||||||||||||
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References
Keywords
