1402702-76-4
Chemical Structure
ST1060
- CAS No.: 1402702-76-4
- Formula:C35H63NO4
- Molecular Weight:561.88
IUPAC Name: N-(4-(4-(heptyloxy)phenyl)-1-hydroxy-2-(hydroxymethyl)butan-2-yl)heptadecanamide
InChIKey: NOTUXXSJABYWJH-UHFFFAOYSA-N
SMILES: CCCCCCCOC1=CC=C(CCC(CO)(NC(CCCCCCCCCCCCCCCC)=O)CO)C=C1
Biological Activity: ST1060, FTY720 (HY-12005) derivative, is a selective ceramide synthase 2 (CerS2) inhibitor. ST1060 can reduce the level of long-chain dihydroceramide (dhCer) catalyzed by CerS2 with IC50 values of 63.6, and 61.3 μM for C24:0 and C24:1[1].
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ST1060 | ST1060, FTY720 (HY-12005) derivative, is a selective ceramide synthase 2 (CerS2) inhibitor. ST1060 can reduce the level of long-chain dihydroceramide (dhCer) catalyzed by CerS2 with IC50 values of 63.6, and 61.3 μM for C24:0 and C24:1
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Keywords