491833-30-8

Genz-123346 free base Chemical Structure
491833-30-8

Chemical Structure

Genz-123346 free base

  • CAS No.: 491833-30-8
  • Formula:C24H38N2O4
  • Molecular Weight:418.57

IUPAC Name: N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)nonanamide

InChIKey: JMNXWOFCUJJYEO-HYBUGGRVSA-N

SMILES: CCCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O

Biological Activity: Genz-123346 free base is an orally available inhibitor of glucosylceramide synthase. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 of 14 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-12744 		Genz-123346 free base 99.57% Genz-123346 free base is an orally available inhibitor of glucosylceramide synthase. Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 of 14 nM.
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