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Chromogenic peptide substrate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	APC (2) Biochemical Assay Reagents (5) Dipeptidyl Peptidase (1) Factor Xa (3) Factor XI (2) Fluorescent Dye (6) HIV Protease (1) Kallikrein (2) PAI-1 (1) Parasite (1) Ser/Thr Protease (3) Thrombin (1)
By Research Areas:	Cardiovascular Disease (1) Infection (1) Metabolic Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Targets Recommended: MARCKS RXFP Receptor Formyl Peptide Receptor (FPR) Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) Connective Peptide CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119244

Gly-Pro-pNA hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-P0021A

D-Lys(Z)-Pro-Arg-pNA diacetate 1 Publications Verification Spectrozyme PCa; Chromozym Pca diacetate	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .

HY-122142A

Pyr-Pro-Arg-pNA hydrochloride S-2366 hydrochloride	APC Factor XI Biochemical Assay Reagents	Others
Pyr-Pro-Arg-pNA (S2366) hydrochloride is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA hydrochloride can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA hydrochloride can be used for measurement of APC amidolytic activity .

HY-P4254

H-Gly-Glu-pNA	PAI-1 Ser/Thr Protease	Others
H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .

HY-137837

D-Ile-Pro-Arg p-nitroanilide dihydrochloride 1 Publications Verification	Biochemical Assay Reagents	Others
D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA) .

HY-P3934

HIV Protease Substrate I	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-126809A

Bz-Pro-Phe-Arg-pNA hydrochloride Bz-PFR-pNA hydrochloride	Factor Xa	Others
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .

HY-138143

N-(p-Tosyl)-GPR-pNA acetate Chromozym-TH	Fluorescent Dye	Others
N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .

HY-P0020A

Tos-Gly-Pro-Arg-ANBA-IPA acetate tos-GPR-ANBA-IPA acetate	Biochemical Assay Reagents	Others
Tos-Gly-Pro-Arg-ANBA-IPA (tos-GPR-ANBA-IPA) acetate is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA acetate can be used for luminescence measurement .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .

HY-122142

Pyr-Pro-Arg-pNA S-2366	APC Factor XI Biochemical Assay Reagents	Others
Pyr-Pro-Arg-pNA (S2366) is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA can be used for measurement of APC amidolytic activity .

HY-P0020

Tos-Gly-Pro-Arg-ANBA-IPA tos-GPR-ANBA-IPA	Biochemical Assay Reagents	Others
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA can be used for luminescence measurement .

HY-126809

Bz-Pro-Phe-Arg-pNA Bz-PFR-pNA	Kallikrein Ser/Thr Protease Parasite Factor Xa	Others
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .

HY-P0021

D-Lys(Z)-Pro-Arg-pNA Chromozym Pca	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .

HY-168378

D-Val-Leu-Lys-pNA S-2251	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (S-2251) is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-168378A

D-Val-Leu-Lys-pNA acetate S-2251 acetate	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA acetate (S-2251 acetate) is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA acetate acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA acetate binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

Cat. No.	Product Name	Type

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

D-Val-Leu-Lys-pNA dihydrochloride

D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride

Fluorescent Dye

D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-P0021A

D-Lys(Z)-Pro-Arg-pNA diacetate 1 Publications Verification Spectrozyme PCa; Chromozym Pca diacetate	Fluorescent Dye
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .

HY-P0021

D-Lys(Z)-Pro-Arg-pNA Chromozym Pca	Fluorescent Dye
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .

Cat. No.	Product Name	Target	Research Area

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-P0021A

D-Lys(Z)-Pro-Arg-pNA diacetate 1 Publications Verification Spectrozyme PCa; Chromozym Pca diacetate	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .

HY-137409

Suc-AAA-pNA	Peptides	Others
Suc-AAA-pNA is a hydrolyzable peptide substrate. Suc-AAA-pNA serves as a chromogenic substrate for porcine pancreatic elastase, and undergoes hydrolysis via a virtual transition state with a minor physical step and a dominant chemical step, thereby forming a stable reactant state .

HY-P4254

H-Gly-Glu-pNA	PAI-1 Ser/Thr Protease	Others
H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .

HY-P3934

HIV Protease Substrate I	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-126809A

Bz-Pro-Phe-Arg-pNA hydrochloride Bz-PFR-pNA hydrochloride	Factor Xa	Others
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .

HY-P0020A

Tos-Gly-Pro-Arg-ANBA-IPA acetate tos-GPR-ANBA-IPA acetate	Biochemical Assay Reagents	Others
Tos-Gly-Pro-Arg-ANBA-IPA (tos-GPR-ANBA-IPA) acetate is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA acetate can be used for luminescence measurement .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .

HY-P0020

Tos-Gly-Pro-Arg-ANBA-IPA tos-GPR-ANBA-IPA	Biochemical Assay Reagents	Others
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA can be used for luminescence measurement .

HY-126809

Bz-Pro-Phe-Arg-pNA Bz-PFR-pNA	Kallikrein Ser/Thr Protease Parasite Factor Xa	Others
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .

HY-P0021

D-Lys(Z)-Pro-Arg-pNA Chromozym Pca	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .

HY-168378A

D-Val-Leu-Lys-pNA acetate S-2251 acetate	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA acetate (S-2251 acetate) is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA acetate acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA acetate binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

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