33 Results for "

Cyclophosphamide hydrate

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "Cyclophosphamide hydrate" in MCE Product Catalog:

78
78 Publications Verification
Cat. No.: HY-17420A
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate
Research Areas:  

Cancer

Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
loading...
    loading...
78
78 Publications Verification
Cat. No.: HY-17420
CAS No.: 50-18-0
Research Areas:  

Cancer

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
loading...
    loading...
13
13 Cited Publications
Cat. No.: HY-117433
CAS No.: 39800-16-3
Purity:  ≥98.0%
4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-137316A
CAS No.: 1566-15-0
Purity:  ≥98.0%
Research Areas:  

Cancer

Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-13679
CAS No.: 19767-45-4
Purity:  99.78%
Synonyms: Mesnum
Research Areas:  

Cancer

Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide .
loading...
    loading...
Cat. No.: HY-137316
CAS No.: 10159-53-2
Research Areas:  

Cancer

Phosphoramide mustard is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard induces DNA damage .
loading...
    loading...
Cat. No.: HY-17420S
CAS No.: 173547-45-0
Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant .
loading...
    loading...
Cat. No.: HY-17420AR
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate (Standard)
Research Areas:  

Cancer

Cyclophosphamide (hydrate) (Standard) is the analytical standard of Cyclophosphamide (hydrate). This product is intended for research and analytical applications. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
loading...
    loading...
Cat. No.: HY-117433S
CAS No.: 1246816-71-6
Purity:  ≥95.0%
4-Hydroperoxy Cyclophosphamide-d4 is the deuterium labeled 4-Hydroperoxy cyclophosphamide. 4-Hydroperoxy cyclophosphamide is the active metabolite form of the proagent Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide has the potential for lymphomas and autoimmune disorders .
loading...
    loading...
Cat. No.: HY-143498
CAS No.: 2411584-25-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells .
loading...
    loading...
Cat. No.: HY-15266
CAS No.: 112827-99-3
Synonyms: PRI 2202; Impurity D of Calcipotriol
Target:  

Drug Derivative VD/VDR

Research Areas:  

Cancer

24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts . 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer .
loading...
    loading...
Cat. No.: HY-W587524
CAS No.: 22788-18-7
Research Areas:  

Cancer

Carboxyphosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420) .
loading...
    loading...
Cat. No.: HY-N16556
CAS No.: 73519-16-1
2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside (Compound 45) is a phenolic compound. 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside can be isolated from Shorea roxburghii. 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside can be used in the research of Cyclophosphamide (HY-17420)-induced peripheral neuropathy .
loading...
    loading...
Cat. No.: HY-P11162
CAS No.: 2758194-43-1
Target:  

FGFR Akt ERK mTOR Apoptosis

Research Areas:  

Inflammation/Immunology

FGF7p is a small molecule peptide and a potential bladder protector. FGF7p can activate downstream signaling pathways of FGFR2 in the urinary tract epithelium (pFRS2α, pAKT and pERK). FGF7p alleviates cyclophosphamide induced apoptosis and tissue damage in urinary tract epithelial cells by activating AKT and its downstream anti apoptotic targets (pBAD, pS6/mTORC1). FGF7p is commonly used in the study of inflammatory conditions .
loading...
    loading...
Cat. No.: HY-118028
CAS No.: 1950-36-3
Purity:  99.99%
Leyk is an orally active Cysteine derivative. Leyk stimulates bone marrow hematopoiesis. Leyk exerts a significant protective effect against cyclophosphamide-induced leukopenia. Leyk can be used in studies related to thrombocytopenia and leukopenia .
loading...
    loading...
Cat. No.: HY-17420S1
CAS No.: 1178903-96-2
Cyclophosphamide-d8 is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
loading...
    loading...
Cat. No.: HY-17420AS
Synonyms: Cyclophosphamide-d8 monohydrate
Cyclophosphamide-d8 (hydrate) is the deuterium labeled Cyclophosphamide hydrate. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities .
loading...
    loading...
Cat. No.: HY-110198
CAS No.: 459841-96-4
Research Areas:  

Inflammation/Immunology

ONO-8130 is an orally active and selective prostanoid EP1 receptor antagonist. ONO-8130 blocks phosphorylation of ERK in the L6 spinal cord. ONO-8130 relieves bladder pain in mice with cyclophosphamide-induced cystitis. ONO-8130 can be used for interstitial cystitis research .
loading...
    loading...
Cat. No.: HY-13679R
CAS No.: 19767-45-4
Synonyms: Mesnum (Standard)
Research Areas:  

Cancer

Sodium 2-mercaptoethanesulfonate (Standard) is the analytical standard of Sodium 2-mercaptoethanesulfonate. This product is intended for research and analytical applications. Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide .
loading...
    loading...
Cat. No.: HY-13679S
CAS No.: 1189479-73-9
Synonyms: Mesnum-d4 sodium
2-Mercaptoethanesulfonate-d4 sodium (Mesnum-d4 sodium) is the deuterium labeled Sodium 2-mercaptoethanesulfonate (HY-13679). Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide .
loading...
    loading...