1. Others
  2. Others
  3. Sodium 2-mercaptoethanesulfonate

Sodium 2-mercaptoethanesulfonate (Synonyms: Sodium 2-mercaptoethanesulfonate; Mesnum)

Cat. No.: HY-13679 Purity: ≥98.0%
Handling Instructions

Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide.

For research use only. We do not sell to patients.

Sodium 2-mercaptoethanesulfonate Chemical Structure

Sodium 2-mercaptoethanesulfonate Chemical Structure

CAS No. : 19767-45-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 g USD 60 In-stock
Estimated Time of Arrival: December 31
10 g USD 95 In-stock
Estimated Time of Arrival: December 31
50 g   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide[1][2].

In Vitro

Mesna (1-1000 μM) reduces H2O2, HOCl and OH• concentrations in a dose-dependent manner, with an IC50 of 32, 21, and 305 μM, respectively in cell-free experiments[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Mesna (150 mg/kg; a single i.p.) protects the rat brain against traumatic injury[1].
Mesna (200 mg/kg; a single i.p.) attenuates the cisplatin-induced ovarian damages in rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male Wistar Albino rats (250-350 g) are suffered traumatic brain injury (TBI)[1]
Dosage: 150 mg/kg
Administration: A single i.p.
Result: Decreased tissue malondialdehyde levels.
Increased the activity of glutathione peroxidase and superoxide dismutase.
Decreased the levels of nitric oxide, nitric oxide synthetase and xanthine oxidase.
Protected the brain tissues well from injury.
Molecular Weight

164.18

Formula

C₂H₅NaO₃S₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (304.54 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0909 mL 30.4544 mL 60.9088 mL
5 mM 1.2182 mL 6.0909 mL 12.1818 mL
10 mM 0.6091 mL 3.0454 mL 6.0909 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: ≥98.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sodium 2-mercaptoethanesulfonate
Cat. No.:
HY-13679
Quantity:
MCE Japan Authorized Agent: