1566-15-0
Chemical Structure
Phosphoramide mustard cyclohexanamine
- CAS No.: 1566-15-0
- Formula:C10H24Cl2N3O2P
- Molecular Weight:320.20
InChIKey: BGTIPRUDEMNRIP-UHFFFAOYSA-N
SMILES: O=P(N(CCCl)CCCl)(N)O.NC1CCCCC1
Biological Activity: Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].
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Phosphoramide mustard cyclohexanamine | 98.0% | Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage. | ||||||||||||||||||||
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Phosphoramide mustard cyclohexanamine (Standard) | ≥98% | Phosphoramide mustard (cyclohexanamine) (Standard) is the analytical standard of Phosphoramide mustard (cyclohexanamine). This product is intended for research and analytical applications. Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage. | ||||||||||||||||||||
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- [1]. Shanthi Ganesan, et al. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. Toxicol Appl Pharmacol. 2015 Feb 1; 282(3): 252–258. [Content Brief]
- [2]. S Genka, et al. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer Chemother Pharmacol. 1990;27(1):1-7. [Content Brief]