1. Cell Cycle/DNA Damage
  2. DNA Alkylator/Crosslinker
  3. Palifosfamide tromethamine

Palifosfamide tromethamine (Synonyms: Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine)

Cat. No.: HY-114577
Handling Instructions

Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.

For research use only. We do not sell to patients.

Palifosfamide tromethamine Chemical Structure

Palifosfamide tromethamine Chemical Structure

CAS No. : 1070409-31-2

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Description

Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.

Molecular Weight

342.16

Formula

C8H22Cl2N3O5P

CAS No.
SMILES

O=P(NCCCl)(NCCCl)O.NC(CO)(CO)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Palifosfamide tromethamine
Cat. No.:
HY-114577
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