2411584-25-1
Chemical Structure
ERCC1-XPF-IN-1
- CAS No.: 2411584-25-1
- Formula:C28H32ClN5O2
- Molecular Weight:506.04
IUPAC Name: 6-chloro-9-((3-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)methyl)-4-hydroxyphenyl)amino)acridin-2-ol
InChIKey: BQWNIOWWZCEWFX-UHFFFAOYSA-N
SMILES: OC1=CC2=C(NC3=CC=C(O)C(CN4CCN(CCN(C)C)CC4)=C3)C5=CC=C(Cl)C=C5N=C2C=C1
Biological Activity: ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ERCC1-XPF-IN-1 | 99.37% | ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells. | ||||||||||||||||||||
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Keywords
