173547-45-0
173547-45-0
Chemical Structure
Cyclophosphamide-d4
- CAS No.: 173547-45-0
- Formula:C7H11D4Cl2N2O2P
- Molecular Weight:265.11
IUPAC Name: 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide-4,4,5,5-d4
InChIKey: CMSMOCZEIVJLDB-RUKOHJPDSA-N
SMILES: ClCCN(CCCl)P1(OCC([2H])([2H])C([2H])([2H])N1)=O
Biological Activity: Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant[1][2].
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Cyclophosphamide-d4 | Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | |||||||||||||||||||||
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Cyclophosphamide-d8 | Cyclophosphamide-d8 is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | |||||||||||||||||||||
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Cyclophosphamide | 99.91% | Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.97
HY-17420ARCyclophosphamide hydrate (Standard) -
Similarity Score 0.85
HY-W7406744-Ketocyclophosphamide -
Similarity Score 0.81
HY-17419A(R)-Ifosfamide -
Similarity Score 0.81
HY-17419RIfosfamide (Standard) -
Similarity Score 0.75
HY-W1057999Bromofosfamide -
Similarity Score 0.75
HY-106796(-)-(S)-Bromofosfamide -
Similarity Score 0.74
HY-1129164-Hydroxyifosfamide -
Similarity Score 0.69
HY-17419S2Ifosfamide-d4-1 -
Similarity Score 0.68
HY-132451S(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Schwartz PS, et al. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells. Mol Pharmacol. 2001 Dec;60(6):1268-1279. [Content Brief]
