173547-45-0
173547-45-0
Chemical Structure
Cyclophosphamide-d4
- CAS No.: 173547-45-0
- Formula:C7H11D4Cl2N2O2P
- Molecular Weight:265.11
IUPAC Name: 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide-4,4,5,5-d4
InChIKey: CMSMOCZEIVJLDB-RUKOHJPDSA-N
SMILES: ClCCN(CCCl)P1(OCC([2H])([2H])C([2H])([2H])N1)=O
Biological Activity: Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant[1][2].
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Cyclophosphamide-d4 | Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | |||||||||||||||||||||
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Cyclophosphamide-d8 | Cyclophosphamide-d8 is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | |||||||||||||||||||||
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Cyclophosphamide | 99.91% | Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Schwartz PS, et al. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells. Mol Pharmacol. 2001 Dec;60(6):1268-1279. [Content Brief]
