(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit
Based on 1 Customer Validation
(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit is the deuterium labeled (R,S)-4-Hydroxy Cyclophosphamide Preparation Kit that can be used to prepare labeled metabolites of cyclophosphamide. (R,S)-4-Hydroxy Cyclophosphamide is an isomer of 4-Hydroxycyclophosphamide, the active metabolite of the cytotoxic alkylating agent Cyclophosphamide (HY-17420).
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 1329838-09-6
- Formula: C7H11D4Cl2N2O3P
- Molecular Weight:281.11
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
The (R,S)-4-Hydroxycyclophosphamide-d4 preparation kit contains one vial of the oxidized precursor and one vial of the reducing agent (2.5 mg sodium thiosulfate).
Before use, add 0.5 mL of sterile water to the vial containing the reducing agent and mix until completely dissolved. Then, transfer the reducing agent solution to the vial labeled (R,S)-4-Hydroxycyclophosphamide-d4 and mix until dissolved; the resulting solution should be used immediately and not allowed to stand for an extended period.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1329838-09-6
-
Unlabeled Cas 2382862-00-0
-
Appearance Solid
-
Molecular Weight 281.11
-
Formula C7H11D4Cl2N2O3P
-
Color White to off-white
-
SMILES
N(CC(Cl)([2H])[2H])(CC(Cl)([2H])[2H])P1(=O)N[C@@H](O)CCO1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Shibata Y, et al. Plausible drug interaction between cyclophosphamide and voriconazole via inhibition of CYP2B6. Drug Metab Pharmacokinet. 2021 Aug;39:100396. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit Related Classifications
HY-132451S Related Classifications
Powered by Bioz