5 Results for "

Dual LCK/SRC inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Dual LCK/SRC inhibitor" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-101053
CAS No.: 179248-59-0
Purity:  99.93%
Synonyms: SRC Kinase inhibitor 1; SRC-l1
Target:  

Src

Research Areas:  

Cancer

Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.
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5
5 Cited Publications
Cat. No.: HY-12299
CAS No.: 837422-57-8
Purity:  99.87%
Synonyms: Dual LCK/SRC inhibitor
Target:  

Src

Research Areas:  

Cancer

WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.
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Cat. No.: HY-18307
CAS No.: 913376-84-8
Target:  

c-Met/HGFR

Research Areas:  

Cancer

SYN1143 is a potent, selective and orally active dual inhibitor of c-Met/RON, with IC50s of 4 and 9 nM, respectively. SYN1143 has weak inhibitory activity on Lck, Tie2, Src, and BTK with IC50s ranging from 160 to 710 nM. SYN1143 can be used for the research of cancers that RON and c-Met are activated .
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Cat. No.: HY-12299G
CAS No.: 837422-57-8
Synonyms: Dual LCK/SRC inhibitor (GMP)
WH-4-023 GMP is WH-4-023 (HY-12299) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. WH-4-023 (Dual LCK/SRC inhibitor) is a Lck/Src dual target inhibitor with functions in stem cell maintenance and differentiation regulation. WH-4-023 blocks epithelial-mesenchymal transition, supports the self-renewal of porcine embryonic stem cells, and inhibits their differentiation into mesoderm and endoderm. WH-4-023 is a key component of 3i/LAF medium, and enables the stable establishment and long-term maintenance of porcine pre-gastrulation epiblast stem cell lines. Removal of WH-4-023 reduces the expression of pluripotency factors in porcine and human extended pluripotent stem cells. WH-4-023 can be applied to relevant studies such as non-small cell lung cancer resistant to EGFR-TKIs .
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Cat. No.: HY-101053R
CAS No.: 179248-59-0
Synonyms: SRC Kinase inhibitor 1 (Standard); SRC-l1 (Standard)
Target:  

Src Reference Standards

Research Areas:  

Cancer

Src Inhibitor 1 (Standard) is the analytical standard of Src Inhibitor 1 (HY-101053). This product is intended for research and analytical applications. Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.
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