4 Results for "

EXP-3174

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "EXP-3174" in MCE Product Catalog:

Losartan Carboxylic Acid
Losartan Carboxylic Acid
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Art. -Nr.: HY-12765
CAS. Nr.: 124750-92-1
Reinheit:  98.95%
Synonyms: E-3174; EXP-3174
Target:  

Drug Metabolite Angiotensin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure .
Losartan-d4 (carboxylic acid)
Losartan-d4 (carboxylic acid)
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Art. -Nr.: HY-12765S
CAS. Nr.: 1246820-62-1
Reinheit:  98.17%
Synonyms: E-3174 d4; EXP-3174 d4
Losartan-d4 carboxylic acid (E-3174-d4) is the deuterium labeled Losartan Carboxylic Acid (HY-12765). Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.
Losartan carboxylic acid-d9
Losartan carboxylic acid-d9
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Art. -Nr.: HY-151001S
CAS. Nr.: 2749283-47-2
Synonyms: E-3174-d9; EXP-3174-d9
EXP3174-d9 is the deuterium labeled EXP3174 .
Losartan Carboxylic Acid (Standard)
Losartan Carboxylic Acid (Standard)
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Art. -Nr.: HY-12765R
CAS. Nr.: 124750-92-1
Synonyms: E-3174 (Standard); EXP-3174 (Standard)
Target:  

Drug Metabolite Reference Standards Angiotensin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure [4].
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