2. Others Metabolic Enzyme/Protease GPCR/G Protein
  3. Drug Metabolite Reference Standards Angiotensin Receptor
  4. Losartan Carboxylic Acid (Standard)

Losartan Carboxylic Acid (Standard)  (Synonyms: E-3174 (Standard); EXP-3174 (Standard))

Art. -Nr.: HY-12765R Reinheit: 98%
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Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[4].

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Losartan Carboxylic Acid (Standard)

Losartan Carboxylic Acid (Standard) Chemische Struktur

CAS. Nr. : 124750-92-1

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Information
Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molekulargewicht

436.89

Formel

C22H21ClN6O2
CAS. Nr.
SMILES

O=C(C1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Losartan Carboxylic Acid (Standard) Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Losartan Carboxylic Acid (Standard)124750-92-1E-3174 (Standard)EXP-3174 (Standard)Drug MetaboliteReference StandardsAngiotensin Receptormetabolitevascularsmoothmusclecellsangiotensin IIanteriormyocardialinfarctionpressorresponsesInhibitorinhibitorinhibit

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