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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
56 Results for "
FHs 74 Int
" in MedChemExpress (MCE) Product Catalog:
Products (56)
56 Results for "FHs 74 Int" in MCE Product Catalog:
86
86 Publications Verification
Synonyms: Int-747; 6-ECDCA; 6-Ethylchenodeoxycholic acid
Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy .
49
49 Cited Publications
Synonyms: S-EMCA
Áreas de investigación:
INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM .
6
6 Cited Publications
Áreas de investigación:
INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively .
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
3
3 Cited Publications
Synonyms: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet
1
1 Cited Publications
Referencia número: HY-P700065AF
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBGF-3; FGF3; Proto-oncogene Int-2; Heparin-binding growth factor 3; Int2; Fibroblast Growth Factor 3
Referencia número: HY-N9445
No. CAS: 13007-32-4
Synonyms: LNnT
Category:
Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
Target:
Referencia número: HY-P99654
No. CAS: 2245205-37-0
Synonyms: Int-001
Target:
Áreas de investigación:
Referencia número: HY-P990059
No. CAS: 2760250-47-1
Synonyms: Int-016; AZD8205 Antibody
Target:
Áreas de investigación:
Referencia número: HY-P991699
No. CAS: 3035710-69-8
Synonyms: AZD9829 antibody; Int-020
Target:
Áreas de investigación:
Synonyms: Int131
Target:
Áreas de investigación:
AMG131 (INT131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor γ modulator (SPPARM). AMG131 binds to PPARγ within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 is promising for research of type-2 diabetes mellitus .
HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells .
Referencia número: HY-P991164
No. CAS: 2975630-15-8
Synonyms: AZD5335 Antibody; Int-019
Target:
Áreas de investigación:
Referencia número: HY-156994
No. CAS: 1426160-58-8
Áreas de investigación:
ASGPR ligand-1 (Compound int-CC2) is an asialoglycoprotein receptor (ASGPR) ligand with a binding Kd value of 0.9 nM. ASGPR ligand-1 is applicable to research on lysosome degradation-related diseases .
Synonyms: S-EMCA R enantiomer
Áreas de investigación:
INT-777 (R-enantiomer) is the R-enantiomer of INT-777, with EC50 of 4.79 μM for TGR5, and less potent than INT-777.
Category:
Target:
Referencia número: HY-34505
No. CAS: 16034-46-1
Referencia número: HY-12222R
No. CAS: 459789-99-2
Synonyms: Int-747 (Standard); 6-ECDCA (Standard); 6-Ethylchenodeoxycholic acid (Standard)
Target:
Áreas de investigación:
Obeticholic acid (Standard) is the analytical standard of Obeticholic acid. This product is intended for research and analytical applications. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy .
Referencia número: HY-148202
No. CAS: 2567770-65-2
Influenza antiviral conjugate-1 (INT-2) is a HIV inhibitor, shows potent cell fusion inhibition . Influenza antiviral conjugate-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
