2975630-15-8
2975630-15-8
Chemical Structure
Torvutatug
Synonym(s): AZD5335 Antibody; INT-019
- CAS No.: 2975630-15-8
- Formula:N/A
- Molecular Weight:(145.532 kDa)
SMILES: [Torvutatug]
Biological Activity: Torvutatug (AZD5335 Antibody) is a human IgG1 κ monoclonal antibody against FRα, with an IC50 value of 7.4 nM against hFRα. Torvutatug can serve as an ADC antibody for the synthesis of ADC, such as AZD5335. Torvutatug is applicable to ovarian cancer-related research[1][2][3].
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Torvutatug | 99% | Torvutatug (AZD5335 Antibody) is a human IgG1 κ monoclonal antibody against FRα, with an IC50 value of 7.4 nM against hFRα. Torvutatug can serve as an ADC antibody for the synthesis of ADC, such as AZD5335. Torvutatug is applicable to ovarian cancer-related research. | ||||||||||||||||||||
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References
- [1]. Zoeller JJ, et al. Derivation of AZD5335, a Novel FRα-Targeted TOP1i-Loaded ADC, for the Treatment of FRα-Expressing Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Dec 15;31(24):5261-5275. [Content Brief]
- [2]. International Nonproprietary Names for Pharmaceutical Substances (INN), WHO Drug Information, Vol. 38 , No. 4, 2024.
- [3]. Moore KN, et al. Antibody-drug conjugates in gynaecological cancers: opportunities and challenges. Nat Rev Clin Oncol. 2026 Jun 17. [Content Brief]
Keywords
