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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
FZD receptor
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "FZD receptor" in MCE Product Catalog:
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2 Cited Publications
F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD) .
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FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=?6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade .
Cat. No.: HY-P10810
Cat. No.: HY-D1474
CAS No.: 33628-03-4
WNT7A-IN-1 sodium (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 sodium significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin . WNT7A-IN-1 sodium (compound F) is also a photographic sensitizer in the green spectral region .
Cat. No.: HY-170411
CAS No.: 29133-39-9
WNT7A-IN-1 (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin. WNT7A-IN-1 (compound F) is also a photographic sensitizer in the green spectral region .
Cat. No.: HY-P10204
CAS No.: 2416664-25-8
Cat. No.: HY-P99582
CAS No.: 1644134-10-0
Synonyms: ONC-005, OTSA101
Target:
Research Areas:
Cat. No.: HY-P702283
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FZD3; Frizzled Family receptor 3; Frizzled Class receptor 3; Frizzled (Drosophila) Homolog 3; Fz-3; Frizzled Homolog 3 (Drosophila); Frizzled-3; Frizzled Homolog 3; Frizzled 3, Seven Transmembrane Spanning receptor; HFz3
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Cat. No.: HY-P78722
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD2; HFz2; Frizzled Class receptor 2; Frizzled (Drosophila) Homolog 2; Frizzled-2; Frizzled Homolog 2 (Drosophila); Frizzled 2, Seven Transmembrane Spanning receptor; Frizzled Homolog 2; Frizzled Family receptor 2; OMOD2; Fz-2; Fz2; FzE2
Cat. No.: HY-P79115
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD9; Frizzled Family receptor 9; Frizzled Class receptor 9; HFz9; FZD3; FzE6; Frizzled-9; Fz-9; CD349; Frizzled (Drosophila) Homolog 9; Frizzled 9, Seven Transmembrane Spanning receptor; Frizzled Homolog 9; Frizzled Homolog 9 (Drosophila); CD349 Antigen
Cat. No.: HY-P70918
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD2; HFz2; Frizzled Class receptor 2; Frizzled (Drosophila) Homolog 2; Frizzled-2; Frizzled Homolog 2 (Drosophila); Frizzled 2, Seven Transmembrane Spanning receptor; Frizzled Homolog 2; Frizzled Family receptor 2; OMOD2; Fz-2; Fz2; FzE2
Cat. No.: HY-P74140
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD4; Frizzled Homolog 4 (Drosophila); Prev. EVR1; Exudative Vitreoretinopathy 1; CD344; WNT receptor Frizzled-4; Frizzled 4, Seven Transmembrane Spanning receptor; Frizzled Homolog 4; Frizzled Family receptor 4; CD344 Antigen; Frizzled-4; FZD4S; Fz-4; FE
Cat. No.: HY-P74141
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD4; Frizzled Homolog 4 (Drosophila); Prev. EVR1; Exudative Vitreoretinopathy 1; CD344; WNT receptor Frizzled-4; Frizzled 4, Seven Transmembrane Spanning receptor; Frizzled Homolog 4; Frizzled Family receptor 4; CD344 Antigen; Frizzled-4; FZD4S; Fz-4; FE
Cat. No.: HY-P74142
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD4; Frizzled Homolog 4 (Drosophila); Prev. EVR1; Exudative Vitreoretinopathy 1; CD344; WNT receptor Frizzled-4; Frizzled 4, Seven Transmembrane Spanning receptor; Frizzled Homolog 4; Frizzled Family receptor 4; CD344 Antigen; Frizzled-4; FZD4S; Fz-4; FE
Cat. No.: HY-P74143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD4; Frizzled Homolog 4 (Drosophila); Prev. EVR1; Exudative Vitreoretinopathy 1; CD344; WNT receptor Frizzled-4; Frizzled 4, Seven Transmembrane Spanning receptor; Frizzled Homolog 4; Frizzled Family receptor 4; CD344 Antigen; Frizzled-4; FZD4S; Fz-4; FE
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
