Fz7-21S
Based on 1 Customer Validation
Fz7-21S is a negative control of Fz7-21. Fz7-21 is a potent peptide antagonist of FZD7 receptors.
For research use only. We do not sell to patients.
- Purity: 98.91%
- CAS No.: 2247635-24-9
- Formula: C83H114N18O24S
- Molecular Weight:1779.96
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2247635-24-9
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Appearance Solid
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Molecular Weight 1779.96
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Formula C83H114N18O24S
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Color White to off-white
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Sequence
Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Ser-His-Val-Met-Tyr-NH2
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Sequence Shortening
Ac-LPSDDLEFWSHVMY-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (56.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Aaron H Nile, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Jun;14(6):582-590. [Content Brief]
[2]. Nile AH, et, al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Jun;14(6):582-590. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5618 mL | 2.8091 mL | 5.6181 mL | 14.0453 mL |
| 5 mM | 0.1124 mL | 0.5618 mL | 1.1236 mL | 2.8091 mL | |
| 10 mM | 0.0562 mL | 0.2809 mL | 0.5618 mL | 1.4045 mL | |
| 15 mM | 0.0375 mL | 0.1873 mL | 0.3745 mL | 0.9364 mL | |
| 20 mM | 0.0281 mL | 0.1405 mL | 0.2809 mL | 0.7023 mL | |
| 25 mM | 0.0225 mL | 0.1124 mL | 0.2247 mL | 0.5618 mL | |
| 30 mM | 0.0187 mL | 0.0936 mL | 0.1873 mL | 0.4682 mL | |
| 40 mM | 0.0140 mL | 0.0702 mL | 0.1405 mL | 0.3511 mL | |
| 50 mM | 0.0112 mL | 0.0562 mL | 0.1124 mL | 0.2809 mL |
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