27 Results for "

Fmoc-NH-PEG2-CH2CH2COOH

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "Fmoc-NH-PEG2-CH2CH2COOH" in MCE Product Catalog:

Cat. No.: HY-W040238
CAS No.: 872679-70-4
Research Areas:  

Cancer

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-41189
CAS No.: 863971-53-3
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers .
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Cat. No.: HY-172320
CAS No.: 2919596-13-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-986238 is an orally active macrocyclic peptide PD-L1 inhibitor. BMS-986238 can be used in the research of tumors such as solid tumors and lymphomas .
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Cat. No.: HY-P10392AF
Target:  

Wnt β-catenin

Research Areas:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-P11295
CAS No.: 3035272-00-2
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-GGFG-PAB-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADC) .
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Cat. No.: HY-P10224A
Target:  

EGFR

Research Areas:  

Cancer

G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .
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Cat. No.: HY-P10896
CAS No.: 1446005-10-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
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Cat. No.: HY-W019682
CAS No.: 84889-09-8
Research Areas:  

Cancer

Fmoc-FF is a building block. Fmoc-FF-prepared hydrogels and nanogels selectively deliver Dexamethasone (HY-14648) to leukemia cells .
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Cat. No.: HY-P10964
CAS No.: 2802416-72-2
Target:  

GHSR

Research Areas:  

Endocrinology

Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .
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Cat. No.: HY-P5037
CAS No.: 185213-75-6
Target:  

Peptides

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp-OH is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-P5962
Target:  

Peptides

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp(OtBu)-OH (TFA) is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers .
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Cat. No.: HY-P5045
CAS No.: 133575-43-6
Research Areas:  

Inflammation/Immunology Cancer

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH inhibits cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening immunologic response .
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Cat. No.: HY-W1050525
CAS No.: 2377585-15-2
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-Val-Ala-Gly (compound 58a) is a cleavable ADC linker, can be conjugated to the antibody Trastuzumab (HY-P9907) to form an antibody-drug conjugate (ADC) .
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Cat. No.: HY-P5037A
Target:  

Peptides

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp-OH TFA is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-P10224
CAS No.: 936728-13-1
Target:  

EGFR

Research Areas:  

Cancer

G7-18NATE is a peptide inhibitor of Grb7. HY-P10224 binds to the Grb7-SH2 domain with micromolar affinity (KD = 18.1 μM). G7-18NATE inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .
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Cat. No.: HY-P5568
CAS No.: 152835-17-1
Synonyms: RP 71955
Target:  

HIV

Research Areas:  

Infection

RP 71955 is an antimicrobial peptide against HIV-1 .
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Cat. No.: HY-P11504
CAS No.: 3109821-26-0
Research Areas:  

Others

Fmoc-Lys-Gly-Dopa-OH is a tripeptide. Fmoc-Lys-Gly-Dopa-OH forms coacervates in aqueous solution via phase separation. Fmoc-Lys-Gly-Dopa-OH coacervates, with the assistance of Fe 3+, provide a viable material to engineer the surface of mammalian cells .
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Cat. No.: HY-P12133
CAS No.: 3080063-21-1
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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