24 Results for "

Furin

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Furin" in MCE Product Catalog:

  • Targets Recommended:
7
7 Publications Verification
Cat. No.: HY-P1028
CAS No.: 673202-67-0
Synonyms: Furin Inhibitor II
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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7
7 Publications Verification
Cat. No.: HY-P1028A
CAS No.: 958204-56-3
Synonyms: Furin Inhibitor II TFA
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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3
3 Cited Publications
Cat. No.: HY-147140
CAS No.: 2387633-15-8
Purity:  98.45%
Target:  

Furin

Research Areas:  

Inflammation/Immunology

BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease .
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2
2 Cited Publications
Cat. No.: HY-P78747
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Furin; FUR; PACE; PCSK3; SPC1
Species:  
Source:  
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Cat. No.: HY-P0133
CAS No.: 143413-47-2
Synonyms: Nona-L-arginine; Peptide R9
Target:  

Ser/Thr Protease

Research Areas:  

Neurological Disease

(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
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Cat. No.: HY-P2469
CAS No.: 1816939-52-2
Synonyms: BNP-45, mouse
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a 45-amino-acid peptide derived from the mouse BNP prohormone, which exhibits natriuretic, diuretic, and vasoactive effects. Brain Natriuretic Peptide-45, mouse contains all amino acid residues deemed critical for the biological activity of natriuretic peptides. Brain Natriuretic Peptide-45, mouse possesses hypotensive and diuretic activities .
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Cat. No.: HY-150737
CAS No.: 2417283-44-2
Purity:  95.08%
Target:  

SARS-CoV

Research Areas:  

Infection

MI-1851 is a potent furin inhibitor. MI-1851 prevents the proteolytic processing of the S protein of SARS-CoV-2 by endogenous flavoprotease in HEK293 cells. MI-185 has antiviral activity .
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Cat. No.: HY-110147B
Purity:  ≥99.0%
Target:  

Furin

Research Areas:  

Infection

SSM3 tetraTFA hydrate is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA hydrate is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .
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Cat. No.: HY-P4548
CAS No.: 136132-77-9
Synonyms: Boc-RVRR-AMC
Target:  

Furin

Research Areas:  

Others

Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
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Cat. No.: HY-P4349A
CAS No.: 1255501-99-5
Research Areas:  

Others

Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide, and a fluorescent substrate. Pyr-Arg-Thr-Lys-Arg-AMC TFA can be used to detect the activity of specific proteases, such as Furin, Trypsin, and Thrombin .
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Cat. No.: HY-P5272
CAS No.: 112844-49-2
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
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Cat. No.: HY-P3797
CAS No.: 174838-79-0
Target:  

Furin

Research Areas:  

Cancer

Furin Substrate is an peptide. Furin Substrate can be used for the research of various biochemical .
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Cat. No.: HY-163738
Target:  

Furin SARS-CoV

Research Areas:  

Infection

Furin-IN-2 (compound P3) is a potent inhibitor of furin, with the IC50 of 35 μM. Furin-IN-2 shows antiviral activity .
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Cat. No.: HY-P4349
CAS No.: 155575-02-3
Research Areas:  

Others

Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide, and a fluorescent substrate. Pyr-Arg-Thr-Lys-Arg-AMC can be used to detect the activity of specific proteases, such as Furin, Trypsin, and Thrombin .
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Cat. No.: HY-RS05148
Research Areas:  

Others

FURIN Human Pre-designed siRNA Set A contains three designed siRNAs for FURIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19197
Research Areas:  

Others

Furin Mouse Pre-designed siRNA Set A contains three designed siRNAs for Furin gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25685
Research Areas:  

Others

Furin Rat Pre-designed siRNA Set A contains three designed siRNAs for Furin gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-110147A
CAS No.: 2320930-10-5
Target:  

Furin

Research Areas:  

Infection

SSM3 tetraTFA is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .
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Cat. No.: HY-180145
CAS No.: 3080672-14-3
Target:  

Furin Influenza Virus

Research Areas:  

Infection

Furin-IN-3 is a non-peptidic furin inhibitor with a dichlorobiphenyl-derived core, with a Ki value of 1.67 nM for furin inhibition and a Ki value of 278 nM for proprotein convertase PC7 inhibition. Furin-IN-3 can be used in the research of influenza A virus infection (H7N7 strain SC35M) .
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Cat. No.: HY-P10150
CAS No.: 749879-64-9
Target:  

Bacterial

Research Areas:  

Infection

IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R .
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