1 Result for "

HY-P1928

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HY-P1928" in MCE Product Catalog:

Cat. No.: HY-P1928
CAS No.: 330936-69-1
Target:  

Bcl-2 Family

Research Areas:  

Neurological Disease Endocrinology

Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging .
Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG .
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