Search Result

Results for "

Heptapeptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin Receptor (4) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (2) Apoptosis (1) Arp2/3 Complex (1) Bacterial (2) Biochemical Assay Reagents (1) Cholecystokinin Receptor (1) Complement System (1) Cytochrome P450 (1) Drug Intermediate (2) Dynamin (1) Endogenous Metabolite (4) Eukaryotic Initiation Factor (eIF) (1) GnRH Receptor (1) HSP (1) Integrin (4) Isotope-Labeled Compounds (1) Neurokinin Receptor (3) Opioid Receptor (4) Peptide-Drug Conjugates (PDCs) (1) PERK (1) Phytohormone (1) PKA (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Transferrin Receptor (1) VEGFR (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (10) Endocrinology (5) Infection (5) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (9)

By Targets:

Angiotensin Receptor (4)

Angiotensin-converting Enzyme (ACE) (3)

Antibiotic (2)

Apoptosis (1)

Arp2/3 Complex (1)

Bacterial (2)

Biochemical Assay Reagents (1)

Cholecystokinin Receptor (1)

Complement System (1)

Cytochrome P450 (1)

Drug Intermediate (2)

Dynamin (1)

Endogenous Metabolite (4)

Eukaryotic Initiation Factor (eIF) (1)

GnRH Receptor (1)

HSP (1)

Integrin (4)

Isotope-Labeled Compounds (1)

Neurokinin Receptor (3)

Opioid Receptor (4)

Peptide-Drug Conjugates (PDCs) (1)

PERK (1)

Phytohormone (1)

PKA (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (3)

Transferrin Receptor (1)

VEGFR (1)

By Research Areas:

Cancer (5)

Cardiovascular Disease (10)

Endocrinology (5)

Infection (5)

Inflammation/Immunology (6)

Metabolic Disease (3)

Neurological Disease (9)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12403

Talfirastide Maximum Cited Publications 17 Publications Verification TXA127; Angiotensin (1-7); Ang-(1-7)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

HY-B0686

Eptifibatide 5+ Cited Publications	Integrin	Cardiovascular Disease
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P10368

P110 heptapeptide	Dynamin Reactive Oxygen Species (ROS)	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases .

HY-P0248

Kemptide 1 Publications Verification	PKA	Metabolic Disease
Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA).

HY-P0244

Dermorphin	Opioid Receptor	Neurological Disease
Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain .

HY-P2031

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

HY-P2314

HAIYPRH hydrochloride	Transferrin Receptor	Cancer
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier .

HY-12403A

Talfirastide acetate Maximum Cited Publications 17 Publications Verification TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

HY-P1540

Angiotensin III, human, mouse	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT₂R) agonist, with IC₅₀s of 0.648 nM and 21.1 nM for AT₂R and AT₁R, respectively.

HY-P1663A

*ATWLPPR Peptide* TFA** 1 Publications Verification	Complement System	Cardiovascular Disease Metabolic Disease
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF₁₆₅ binding to NRP-1, used in the research of angiogenesis . ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .

HY-B0686B

Eptifibatide acetate 5+ Cited Publications	Integrin	Cardiovascular Disease
Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P1663

ATWLPPR Peptide 1 Publications Verification	VEGFR	Others
ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)

HY-P3890A

Substance P (5-11) TFA	Neurokinin Receptor	Neurological Disease
Substance P (5-11) TFA TFA, the C-terminal heptapeptide of Substance P (HY-P0201), is a neuropeptide. Substance P (5-11) TFA TFA binds to NK-1 tachykinin receptor .

HY-P3675

LH-RH (4-10)	GnRH Receptor	Endocrinology
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .

HY-P3890

Substance P (5-11)	Neurokinin Receptor	Neurological Disease
Substance P (5-11), the C-terminal heptapeptide of Substance P (HY-P0201), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor .

HY-W269700

Ile-Leu-OH L-Isoleucyl-L-leucine	Drug Intermediate	Neurological Disease
Ile-Leu-OH (L-Isoleucyl-L-leucine) is a hydrophobic dipeptide fragment and is a component of the neurotensin C-terminal heptapeptide Pro-Arg-Arg-Pro-Tyr-Ile-LeuOH .

HY-P0244A

Dermorphin TFA	Opioid Receptor	Neurological Disease
Dermorphin TFA is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain .

HY-P2627

CCK (27-33)	Cholecystokinin Receptor	Others
CCK (27-33) is the C-terminal heptapeptide of cholecystokinin (CCK) .

HY-P4196

Met-Enkephalin-Arg-Phe	Opioid Receptor	Neurological Disease
Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity .

HY-B0686A

Eptifibatide monoacetate	Integrin	Cardiovascular Disease
Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P10757

DTX-P7	Peptide-Drug Conjugates (PDCs) Apoptosis HSP Eukaryotic Initiation Factor (eIF) PERK	Cancer
DTX-P7 is a peptide-drug conjugate. DTX-P7, composed of Docetaxel (DTX, HY-B0011) and a heptapeptide (P7), induces unfolded protein response and subsequent apoptosis by degrading Hsp90 .

HY-P6079

Ac-IHIHIYI-NH2	Biochemical Assay Reagents	Neurological Disease
Ac-IHIHIYI-NH2 is a fibrous heptapeptide that forms fibril-like structures with even higher esterase activity .

HY-P1577

Dermorphin Analog	Opioid Receptor	Inflammation/Immunology
Dermorphin Analog is an analog of Dermorphin. Dermorphin is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin.

HY-129613

Rhizonin A	Phytohormone	Others
Rhizonin A is a cyclic heptapeptide that can be isolated from Rhizopus micro-sporus van Tieghem and can promote plant growth .

HY-P10588

WIN 66306	Neurokinin Receptor	Others
WIN 66306 is a cyclic heptapeptide that can be isolated from an Aspergillus species. WIN 66306 is a neurokinin antagonist with antagonistic effects on both NK1 and NK2 receptors .

HY-B0686BR

Eptifibatide acetate (Standard)	Reference Standards Integrin	Cardiovascular Disease
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-108881R

Troleandomycin (Standard) Triacetyloleandomycin (Standard)	Antibiotic Reference Standards Cytochrome P450 Bacterial	Infection Inflammation/Immunology
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-136821

Polymyxin D2	Bacterial Antibiotic	Infection
Polymyxin D2 is an antibiotic discovered from Bacillus polymyxa, exhibiting antibacterial activity. Its core structure consists of a cyclic heptapeptide moiety and a tripeptide side chain with a fatty acyl residue. Polymyxin D2 can be used in anti-infective research .

HY-W269700S

Ile-(Leu-13C6,15N)-OH TFA L-Isoleucyl-L-leucine-¹³C₆,¹⁵N	Isotope-Labeled Compounds Drug Intermediate	Neurological Disease
Ile-(Leu-13C6,15N)-OH TFA is ¹³C- and ¹⁵N-labeled Ile-Leu-OH (HY-W269700). Ile-Leu-OH is a hydrophobic dipeptide fragment and is a component of the neurotensin C-terminal heptapeptide Pro-Arg-Arg-Pro-Tyr-Ile-LeuOH .

HY-12403R

Talfirastide (Standard) TXA127 (Standard); Angiotensin (1-7) (Standard); Ang-(1-7) (Standard)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite Reference Standards	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Talfirastide (Standard) is the analytical standard of Talfirastide. This product is intended for research and analytical applications. Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

HY-P10830

AT1R epitope	Endogenous Metabolite	Infection
AT1R epitope (iCF10), a heptapeptide, is a competitive cCF10 (a peptide pheromone) inhibitor .

Cat. No.	Product Name	Target	Research Area