Search Result

Results for "

Heterocyclic compounds

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Isotope-Labeled Compounds (11) 11β-HSD (1) Antibiotic (1) Apoptosis (5) Aryl Hydrocarbon Receptor (3) Bacterial (13) Biochemical Assay Reagents (23) CDK (1) Complement System (4) Drug Derivative (8) Drug Intermediate (35) EGFR (2) Endogenous Metabolite (16) Environmental Pollutants (2) Epigenetic Reader Domain (1) ER-phagy (1) Estrogen Receptor/ERR (1) Fluorescent Dye (2) Fungal (3) GLP Receptor (1) Glucocorticoid Receptor (1) GSK-3 (2) HIV (3) hnRNP (1) iGluR (2) Lipocalin Family (1) LRRK2 (2) Microtubule/Tubulin (1) Mineralocorticoid Receptor (1) MOFs (3) Monoamine Oxidase (2) p38 MAPK (3) Parasite (4) Phosphodiesterase (PDE) (1) PROTACs (1) Ras (1) Reactive Oxygen Species (ROS) (3) Reference Standards (15) Reverse Transcriptase (1) Ser/Thr Protease (3) Thrombopoietin Receptor (3) Xanthine Oxidase (2)
By Research Areas:	Cancer (32) Cardiovascular Disease (4) Endocrinology (3) Infection (30) Inflammation/Immunology (16) Metabolic Disease (11) Neurological Disease (11)

By Targets:

Isotope-Labeled Compounds (11)

11β-HSD (1)

Antibiotic (1)

Apoptosis (5)

Aryl Hydrocarbon Receptor (3)

Bacterial (13)

Biochemical Assay Reagents (23)

CDK (1)

Complement System (4)

Drug Derivative (8)

Drug Intermediate (35)

EGFR (2)

Endogenous Metabolite (16)

Environmental Pollutants (2)

Epigenetic Reader Domain (1)

ER-phagy (1)

Estrogen Receptor/ERR (1)

Fluorescent Dye (2)

Fungal (3)

GLP Receptor (1)

Glucocorticoid Receptor (1)

GSK-3 (2)

HIV (3)

hnRNP (1)

iGluR (2)

Lipocalin Family (1)

LRRK2 (2)

Microtubule/Tubulin (1)

Mineralocorticoid Receptor (1)

MOFs (3)

Monoamine Oxidase (2)

p38 MAPK (3)

Parasite (4)

Phosphodiesterase (PDE) (1)

PROTACs (1)

Ras (1)

Reactive Oxygen Species (ROS) (3)

Reference Standards (15)

Reverse Transcriptase (1)

Ser/Thr Protease (3)

Thrombopoietin Receptor (3)

Xanthine Oxidase (2)

By Research Areas:

Cancer (32)

Cardiovascular Disease (4)

Endocrinology (3)

Infection (30)

Inflammation/Immunology (16)

Metabolic Disease (11)

Neurological Disease (11)

119

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Isotope-Labeled Compounds ATTECs

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W001132

Indole 2 Publications Verification	Environmental Pollutants Endogenous Metabolite	Infection
Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

HY-Y0091

Xantphos 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene	Biochemical Assay Reagents	Others
Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a bisphosphine ligand. Xantphos coordinates to metals in either cis or trans chelation mode. Xantphos acts as a key ligand in palladium or platinum catalyzed reactions. Xantphos can be used in the construction of heterocyclic compounds in organic synthesis .

HY-Y0061

Oxindole 3 Publications Verification 2-Indolinone	HIV Endogenous Metabolite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.

HY-W017289

4,4′-Dipyridyl	Drug Intermediate	Others
4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide .

HY-W007355

Skatole Maximum Cited Publications 6 Publications Verification 3-Methylindole; 3-Methyl-1H-indole	Environmental Pollutants Apoptosis Endogenous Metabolite p38 MAPK Aryl Hydrocarbon Receptor	Others
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-W013040

Pyrazine 1,4-Diazine	MOFs Drug Intermediate	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .

HY-40294

Indazole	Monoamine Oxidase GSK-3 LRRK2	Cardiovascular Disease Neurological Disease Cancer
Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases .

HY-N6856

4-Hydroxycoumarin	Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-76228

1H-pyrazole Pyrazole	Parasite iGluR	Infection
1H-pyrazole (Pyrazole) is a five-membered heterocyclic compound, and its derivatives are orally effective antimalarial and antileishmanial agents with the potential to modulate targets such as alcohol dehydrogenase and NMDA receptors. 1H-pyrazole derivatives exhibit inhibitory effects on Plasmodium berghei in infected mice and on promastigotes of Leishmania aethiopica, respectively. 1H-pyrazole can be used in research related to malaria and leishmaniasis .

HY-21179

Trimethylsilyl trifluoromethylsulfonate	Biochemical Assay Reagents	Others
Trimethylsilyl trifluoromethylsulfonate is a metal-free catalyst. Trimethylsilyl trifluoromethylsulfonate can be used for the synthesis of biologically active fluorinated heterocyclic compounds .

HY-W018800

4(3H)-Quinazolinone 1 Publications Verification	Bacterial EGFR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-103656

Tetraphenylporphyrin TPP; Tetraphenylporphine; meso-Tetraphenylporphyrin	MOFs	Cancer
Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .

HY-W002457

3-Nitropyrazole	Biochemical Assay Reagents Drug Intermediate	Others
3-Nitropyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Nitropyrazole is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .

HY-Y0519

Pyrimidine	Endogenous Metabolite	Neurological Disease Cancer
Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W003165

3-Bromo-5-chloropyridine	Biochemical Assay Reagents	Others
3-Bromo-5-chloropyridine is a widely used heterocyclic compound that can be used to synthesize compounds. 3-Bromo-5-chloropyridine can be used as an intermediate in the production of crop protectants in the agricultural chemicals industry. 3-Bromo-5-chloropyridine can participate in cross-coupling reactions .

HY-W002016

Phthalazine	Reactive Oxygen Species (ROS)	Cancer
Phthalazine is a substrate for human aldehyde oxidase 1, which can lead to the production of ROS and subsequent enzyme inactivation. Phthalazine is a nitrogen-containing organic heterocyclic compound. Phthalazine exhibits antitumor activity in blood cancer, breast cancer, colon cancer, lung cancer and renal cancer .

HY-145412

GLP-1 receptor agonist 7	GLP Receptor	Metabolic Disease
GLP-1 receptor agonist 7 (Compound 130b) is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 7 generates cAMP under the mediation of GLP-1R with an EC₅₀ of ≤ 0.2 nM. GLP-1 receptor agonist 7 can be used to study diseases related to the GLP-1 receptor (particularly type 2 diabetes) .

HY-41340

2-Aminopyrimidine	Biochemical Assay Reagents Drug Intermediate	Others
2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds .

HY-Y0410

2-Aminobenzimidazole 2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine	Biochemical Assay Reagents	Others
2-Aminobenzimidazole (2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine) is a heterocyclic aromatic compound. 2-Aminobenzimidazole is a kind of biological materials or organic compounds that are widely used in life science research .

HY-145657

Benzoquinoquinoxaline BQQ	Biochemical Assay Reagents	Others
Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure .

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Bacterial	Infection
4'-Hydroxy-3'-methylacetophenone is a phenolic volatile compound. 4'-Hydroxy-3'-methylacetophenone can be isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone is believed to possess potent antioxidant activity similar to that of other phenolic volatile compounds, Thymol (HY-N6810) and Eugenol (HY-N0337). 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-W011579

4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone	Biochemical Assay Reagents	Others
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone, is a heterocyclic compound with a five-membered ring structure, which can be used as a starting material for organic synthesis, a reagent for organic transformation, and a biological probe for studying biological processes. 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .

HY-W039724

Thioxanthone	Biochemical Assay Reagents	Others
Thioxanthone is a powerful photocatalyst for organic reactions. Thioxanthone is a heterocyclic compound with the ability to participate successfully in merger reactions with metal complexes .

HY-W140956

3-Methyluracil	Drug Intermediate	Others
3-Methyluracil is a pyrimidine heterocyclic compound that can serve as an intermediate. 3-Methyluracil can be isolated from Cordyceps bassiana .

HY-W010628

Azetidine hydrochloride Trimethyleneimine hydrochloride	Biochemical Assay Reagents Drug Intermediate	Others
Azetidine (Trimethyleneimine) hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Azetidine hydrochloride is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .

HY-W355129S

MeIQx-d3	Isotope-Labeled Compounds	Cancer
MeIQx-d3 is the deuterium labeled MeIQx (HY-W355129) . MeIQx is a heterocyclic amine (HAs) compound and a dietary aromatic amine, which can bind covalently to hemoglobin. MeIQx is a mutagenic compound that induces liver tumors .

HY-66029

6-(Trifluoromethyl)nicotinic acid	Biochemical Assay Reagents	Others
6-(Trifluoromethyl)nicotinic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 6-(Trifluoromethyl)nicotinic acid is a small heterocyclic molecule containing carboxylic acid and trifluoromethyl groups, which can be used as a multifunctional additive .

HY-W003601

2-Bromo-4-fluoropyridine	Biochemical Assay Reagents	Others
2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.

HY-W001132R

Indole (standard) 2 Publications Verification	Reference Standards Endogenous Metabolite	Infection
Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

HY-W100491

Trimethylbenzoquinone	Drug Derivative	Cancer
Trimethylbenzoquinone (Compound 5) is a methylated benzoquinone. Trimethylbenzoquinone exhibits moderate cytotoxicity against K562 cells, with its IC₅₀ being 0.75 μM. Trimethylbenzoquinone is completely unable to cause inter-strand DNA cross-linking and cannot alkylate DNA guanines. Trimethylbenzoquinone can be used to study the relationship between the nitrogen heterocyclic group and DNA cross-linking .

HY-76779

4-(Chloromethyl)-7-hydroxycoumarin	Drug Derivative	Cancer
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .

HY-W016568

Isoxanthopterin	Endogenous Metabolite	Others
Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .

HY-W010627

2,5-Dimethylpyrrole	Drug Intermediate	Others
2,5-Dimethylpyrrole is an aromatic heterocyclic compound. 2,5-Dimethylpyrrole as an important intermediate, and can be used in the synthesis of other active compounds .

HY-W016331

9H-Carbazol-4-ol 4-Hydroxycarbazole	Biochemical Assay Reagents	Others
9H-Carbazol-4-ol (4-Hydroxycarbazole) can be used as an aromatic heterocyclic compound with widespread applications in organic synthesis, as well as certain biochemical and physiological effects. 9H-Carbazol-4-ol is a kind of biological materials or organic compounds that are widely used in life science research .

HY-69360

2,5-Dibromothiazole	Biochemical Assay Reagents	Others
2,5-Dibromothiazole is a heterocyclic compound. 2,5-Dibromothiazole is a key intermediate in organic synthesis .

HY-W013409

2,4-Dichlorobenzenesulfonyl chloride	Bacterial	Infection Cancer
2,4-Dichlorobenzenesulfonyl chloride (Compound 6d) is a heterocyclic building block, which can be used in the synthesis of nicotinyl arylsulfonylhydrazides with anticancer and antibacterial activities .

HY-75637

3-Amino-5-methylpyrazole	Drug Intermediate	Others
5-Methyl-1H-pyrazol-3-amine is a pyrazole heterocyclic compound and can be used as a key intermediate for the synthesis of pyrazolylamide derivatives.

HY-30012

5-Bromo-7-azaindole	Biochemical Assay Reagents Drug Intermediate	Others
5-Bromo-7-azaindole is an important intermediate. 5-Bromo-7-azaindole can be used for the synthesis of other nitrogen-containing heterocyclic compounds .

HY-W016825

2-(Pyridin-2-yl)acetic acid hydrochloride	Drug Intermediate	Others
2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex .

HY-44087

Ethyl (E)-3-(1-pyrrolidinyl)crotonate	Drug Intermediate	Others
Ethyl (E)-3-(1-pyrrolidinyl)crotonate is an organic synthetic intermediate of the enamine ester type. Ethyl (E)-3-(1-pyrrolidinyl)crotonate has a stable structure and strong reactivity, and is mainly used for the construction of heterocyclic compounds and drug molecules.

HY-Y0141

3-Amino-6-chloropyridazine	Drug Intermediate	Others
3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .

HY-W002458

4-Nitropyrazole	Drug Intermediate	Others
4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease .

HY-W010540

4,5-Dimethylthiazole	Drug Intermediate	Others
4,5-Dimethylthiazole is a nitrogen-containing heterocyclic compound. 4,5-Dimethylthiazole can be used in the synthesis of other active compounds .

HY-W024652

4,5-Dimethylimidazole	Drug Intermediate	Others
4,5-Dimethylimidazole is a nitrogen-containing heterocyclic compound and is a synthetic intermediate .

HY-W015966

3-Methylpyrrole	Drug Derivative	Metabolic Disease
3-Methylpyrrole is a pyrrole-type nitrogen-containing heterocyclic aromatic compound. 3-Methylpyrrole can be used as a negative control tool for hexosamine detection .

HY-Y0519R

Pyrimidine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-D1343

DMNPE-caged D-luciferin	Fluorescent Dye
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.

HY-W002277

1,8-Naphthyridine	Drug Derivative	Infection Cancer
1,8-Naphthyridine is a heterocyclic compound with antibacterial and antitumor activities. 1,8-Naphthyridine is promising for research of antibacterial agents and cancers .

HY-W009194

(R)-(+)-Trityl glycidyl ether	Drug Intermediate	Infection
(R)-(+)-Trityl glycidyl ether, a heterocyclic compound, is a precursor that can be used to synthesize glycerophospholipids, as well as compounds with antiviral and antimalarial activities .

HY-65254

5-Amino-2-fluoropyridine	Biochemical Assay Reagents Drug Intermediate	Others
5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .

Cat. No.	Product Name

HY-L138

Heterocyclic Compound Library

6,484 compounds

Heterocyclic compounds are cyclic organic compounds which contain at least one hetero atom, the most common heteroatoms are nitrogen, oxygen ,and sulfur. Heterocycles are common in biology, featuring a wide range of structures from enzyme co-factors to amino acids and proteins. On the one hand, heterocycles are common structural units in approved drugs and in medicinal chemistry targets in the drug discovery process. In addition, heterocycles have been found as a key structure in medical chemistry and also they are frequently found in large percent of biomolecules such as vitamins, natural products ,and biologically active compounds including antifungal, anti-inflammatory, antibacterial, antioxidant, antiallergic, anti-HIV, antidiabetic, anticancer activity.

MCE offers a unique collection of 6,484 heterocyclic compounds which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE heterocyclic compound library is critical for drug discovery and development.

HY-L0094V

Chinese National Compound Library	1,398,968 compounds
The Chinese National Compound Library (CNCL) composes 1.4 million compounds possessing diversified structures. Coupled with this library will be advanced sample handling, information management and quality control systems. Most compounds in the library are drug-like, conforming to “Lipinski’s Rule of Five”, such as MW < 500, logP < 5, Hydrogen Bond Donors < 5.

HY-LD002

DEL B Kit Regular Library

100 billion compounds

The discovery of hit molecule is a cornerstone of drug development. Among the diverse tools available, DNA-encoded libraries have emerged a revolutionary platform for high-throughput screening. Compared with traditional HTS, DEL features shorter screening processes, lower costs, simpler assays, and larger library capacities.

DEL Construction utilizes split-and-pool synthesis, a combinatorial chemistry approach that involves iterative splitting, reaction, and pooling. This strategy enables rapid, exponential assembly of fragments in minimal steps without the need for individual compound synthesis andassoicicated isolation or purification steps, thus greatly reducing overall costs. The technology enables simultaneous affinity screeningof massive compound collections to target proteins in a single step. By coupling chemical structures with unique DNA barcodes, each compound is tagged with a distinct DNA sequence for convenient tracking and decoding.DELs readily enable the construction and efficient screening of libraries containing millions to billions of compounds. As a result, DEL screening combines the dual advantages of high efficiency and low cost, making DEL a transformative technology in modern drug discovery.

The DEL kit consists of 50 independent libraries with a total scale of 100 billion compounds. It is constructed through stepwise combinatorial chemistry strategies involving 2-, 3-, and 4-round synthesis. By employing diverse scaffolds and flexible linking strategies, it encompasses various ring systems, linear frameworks, and heterocyclic structures. Screening can be achieved solely through affinity, independent of target-specific activity detection methods. This library is suitable for DEL screening against a wide range of targets.

HY-L0105V

InterBioScreen Synthetic Compounds Library	485,000 compounds
InterBioScreen Synthetic Compounds Library contains about 485,000 immediately available compounds. The library is generated by very rigorously selecting the most interesting classes of compounds that are most likely to become new drugs or plant protection agents or veterinary preparations.

Cat. No.	Product Name	Type

HY-D0827

Cy2

Cyanine2

Fluorescent Dyes

Cyanines are formally compounds with two nitrogen atoms linked by an odd number of methene units. 26 28 The nitrogen atoms are parts of the heterocyclic units (such as indole, benzoxazol, or benzothiazol) . The structures and optical properties of representative cyanine dyes used for in vivo imaging are presented . Cyanines are characterized by long wavelength, tunable absorption and emission, very high extinction coefficient (up to 300,000 M 1 cm 1), good water solubility, and relatively straightforward synthesis .

HY-D1343

DMNPE-caged D-luciferin	Fluorescent Dyes
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.

Cat. No.	Product Name	Type

HY-D0837

Imidazole

2 Publications Verification

Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Biochemical Assay Reagents

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-Y0091

Xantphos 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene	Biochemical Assay Reagents
Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a bisphosphine ligand. Xantphos coordinates to metals in either cis or trans chelation mode. Xantphos acts as a key ligand in palladium or platinum catalyzed reactions. Xantphos can be used in the construction of heterocyclic compounds in organic synthesis .

HY-W017289

4,4′-Dipyridyl	Biochemical Assay Reagents
4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide .

HY-W002457

3-Nitropyrazole	Biochemical Assay Reagents
3-Nitropyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Nitropyrazole is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .

HY-W003165

3-Bromo-5-chloropyridine	Biochemical Assay Reagents
3-Bromo-5-chloropyridine is a widely used heterocyclic compound that can be used to synthesize compounds. 3-Bromo-5-chloropyridine can be used as an intermediate in the production of crop protectants in the agricultural chemicals industry. 3-Bromo-5-chloropyridine can participate in cross-coupling reactions .

HY-41340

2-Aminopyrimidine	Biochemical Assay Reagents
2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds .

HY-Y0410

2-Aminobenzimidazole 2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine	Biochemical Assay Reagents
2-Aminobenzimidazole (2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine) is a heterocyclic aromatic compound. 2-Aminobenzimidazole is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W011579

4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone

Biochemical Assay Reagents

4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone, is a heterocyclic compound with a five-membered ring structure, which can be used as a starting material for organic synthesis, a reagent for organic transformation, and a biological probe for studying biological processes. 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .

HY-W010628

Azetidine hydrochloride Trimethyleneimine hydrochloride	Biochemical Assay Reagents
Azetidine (Trimethyleneimine) hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Azetidine hydrochloride is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .

HY-66029

6-(Trifluoromethyl)nicotinic acid	Biochemical Assay Reagents
6-(Trifluoromethyl)nicotinic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 6-(Trifluoromethyl)nicotinic acid is a small heterocyclic molecule containing carboxylic acid and trifluoromethyl groups, which can be used as a multifunctional additive .

HY-W003601

2-Bromo-4-fluoropyridine	Biochemical Assay Reagents
2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.

HY-W016331

9H-Carbazol-4-ol 4-Hydroxycarbazole	Biochemical Assay Reagents
9H-Carbazol-4-ol (4-Hydroxycarbazole) can be used as an aromatic heterocyclic compound with widespread applications in organic synthesis, as well as certain biochemical and physiological effects. 9H-Carbazol-4-ol is a kind of biological materials or organic compounds that are widely used in life science research .

HY-69360

2,5-Dibromothiazole	Biochemical Assay Reagents
2,5-Dibromothiazole is a heterocyclic compound. 2,5-Dibromothiazole is a key intermediate in organic synthesis .

HY-75637

3-Amino-5-methylpyrazole	Biochemical Assay Reagents
5-Methyl-1H-pyrazol-3-amine is a pyrazole heterocyclic compound and can be used as a key intermediate for the synthesis of pyrazolylamide derivatives.

HY-30012

5-Bromo-7-azaindole	Biochemical Assay Reagents
5-Bromo-7-azaindole is an important intermediate. 5-Bromo-7-azaindole can be used for the synthesis of other nitrogen-containing heterocyclic compounds .

HY-W016825

2-(Pyridin-2-yl)acetic acid hydrochloride	Biochemical Assay Reagents
2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex .

HY-44087

Ethyl (E)-3-(1-pyrrolidinyl)crotonate	Biochemical Assay Reagents
Ethyl (E)-3-(1-pyrrolidinyl)crotonate is an organic synthetic intermediate of the enamine ester type. Ethyl (E)-3-(1-pyrrolidinyl)crotonate has a stable structure and strong reactivity, and is mainly used for the construction of heterocyclic compounds and drug molecules.

HY-Y0141

3-Amino-6-chloropyridazine	Biochemical Assay Reagents
3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .

HY-W002458

4-Nitropyrazole	Biochemical Assay Reagents
4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease .

HY-Y0425

Terephthalaldehyde

Biochemical Assay Reagents

Terephthalaldehyde is a crosslinking agent. Terephthalaldehyde forms a crosslinked structure inside the gelatin matrix by forming Schiff base imines with the amino groups of gelatin, thereby constructing a three-dimensional network. Terephthalaldehyde improves the hydrophobicity of the gelatin matrix, delays water vapor penetration and enhances the liquid water resistance of gelatin films. Terephthalaldehyde can be used as a crosslinking agent to prepare crosslinked chitosan hydrogel (CAAT) via ultrasound-induced synthesis. Terephthalaldehyde helps CAAT hydrogels selectively adsorb anionic dyes from aqueous media, including multi-component systems containing cationic dyes. Terephthalaldehyde serves as a starting material for the synthesis of bis-heterocyclic compounds (including bis-thiazole and bis-triazolopyrimidine compounds) .

HY-65254

5-Amino-2-fluoropyridine	Biochemical Assay Reagents
5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .

HY-32828

3-Amino-5-bromo-2-chloropyridine	Biochemical Assay Reagents
3-Amino-5-bromo-2-chloropyridine is a nitrogen-containing heterocyclic organic compound. 3-Amino-5-bromo-2-chloropyridine is an important intermediate, which can be used for the synthesis of other active compounds .

HY-W001851

1-Benzylpyrrole-2,5-dione N-Benzylmaleimide	Biochemical Assay Reagents
1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).

HY-D0837R

Imidazole (Standard)

Glyoxaline (Standard); 1,3-Diaza-2,4-cyclopentadiene (Standard)

Biochemical Assay Reagents

Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-D0910

5-Bromo-6-chloro-1H-indol-3-yl acetate

Biochemical Assay Reagents

5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

HY-41340R

2-Aminopyrimidine (Standard)	Biochemical Assay Reagents
2-Aminopyrimidine (Standard) is the analytical standard of 2-Aminopyrimidine (HY-41340). This product is intended for research and analytical applications. 2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W001132

Indole 2 Publications Verification	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification	Environmental Pollutants Endogenous Metabolite
Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

HY-Y0061

Oxindole 3 Publications Verification 2-Indolinone	Neurological Disease Classification of Application Fields Metabolic Disease Plants Endogenous metabolite Indole Alkaloids Infection Alkaloids Human Gut Microbiota Metabolites other families Disease Research Fields Endocrinology Source Classification	HIV Endogenous Metabolite
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.

HY-W007355

Skatole Maximum Cited Publications 6 Publications Verification 3-Methylindole; 3-Methyl-1H-indole	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Apoptosis Endogenous Metabolite p38 MAPK Aryl Hydrocarbon Receptor
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-N6856

4-Hydroxycoumarin	Infection Classification of Application Fields Coumarins Phenylpropanoids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-76228

1H-pyrazole Pyrazole	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Parasite iGluR
1H-pyrazole (Pyrazole) is a five-membered heterocyclic compound, and its derivatives are orally effective antimalarial and antileishmanial agents with the potential to modulate targets such as alcohol dehydrogenase and NMDA receptors. 1H-pyrazole derivatives exhibit inhibitory effects on Plasmodium berghei in infected mice and on promastigotes of Leishmania aethiopica, respectively. 1H-pyrazole can be used in research related to malaria and leishmaniasis .

HY-W018800

4(3H)-Quinazolinone 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Metabolic Disease Quinoline Alkaloids Plants Infection Alkaloids Acanthaceae Disease Research Fields Endocrinology Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	Bacterial EGFR
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-Y0519

Pyrimidine	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L. Source Classification	Bacterial
4'-Hydroxy-3'-methylacetophenone is a phenolic volatile compound. 4'-Hydroxy-3'-methylacetophenone can be isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone is believed to possess potent antioxidant activity similar to that of other phenolic volatile compounds, Thymol (HY-N6810) and Eugenol (HY-N0337). 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-W140956

3-Methyluracil	Structural Classification Caprifoliaceae Cordyceps bassiana Ketones, Aldehydes, Acids Plants Source Classification	Drug Intermediate
3-Methyluracil is a pyrimidine heterocyclic compound that can serve as an intermediate. 3-Methyluracil can be isolated from Cordyceps bassiana .

HY-W001132R

Indole (standard) 2 Publications Verification	Alkaloids Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Indole Alkaloids Source Classification	Reference Standards Endogenous Metabolite
Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

HY-W016568

Isoxanthopterin	Natural Products Animals Source Classification	Endogenous Metabolite
Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .

HY-W007355R

Skatole (Standard) 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis
Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-N6856R

4-Hydroxycoumarin (Standard)	Structural Classification Coumarins Phenylpropanoids Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-Y0519R

Pyrimidine (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W018800R

4(3H)-Quinazolinone (Standard)	Alkaloids Structural Classification Acanthaceae Quinoline Alkaloids Plants Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	Reference Standards Bacterial EGFR
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-N13197

6-Methyl-5,6-dihydro-2H-pyran-2-one	Natural Products Microorganisms Source Classification	Antibiotic Bacterial Fungal Parasite
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-N10000

Hirudonucleodisulfide B	Animals Ketones, Aldehydes, Acids Source Classification	Others
Hirudonucleodisulfide B is a heterocyclic compound that can be found in Whitmania pigra. Hirudonucleodisulfide B shows moderately anti-anoxic activity .

HY-Y0061R

Oxindole (Standard) 2-Indolinone (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites other families Plants Endogenous metabolite Indole Alkaloids Source Classification	Reference Standards HIV Endogenous Metabolite
Oxindole (Standard) is the analytical standard of Oxindole. This product is intended for research and analytical applications. Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.

HY-Y0191R

α-Pyridone (Standard) 2-Pyridone (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Bacterial
α-Pyridone (Standard) is the analytical standard of α-Pyridone. This product is intended for research and analytical applications. α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds .

HY-N3373R

Loganetin (Standard)	Structural Classification Human Gut Microbiota Metabolites Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Plants Endogenous metabolite Source Classification	Reference Standards Bacterial
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-76228R

1H-pyrazole (Standard) Pyrazole (Standard)	Alkaloids Structural Classification Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Parasite iGluR
1H-pyrazole (Standard) is the analytical standard of 1H-pyrazole. This product is intended for research and analytical applications. 1H-pyrazole (Pyrazole) is a five-membered heterocyclic compound, and its derivatives are orally effective antimalarial and antileishmanial agents with the potential to modulate targets such as alcohol dehydrogenase and NMDA receptors. 1H-pyrazole derivatives exhibit inhibitory effects on Plasmodium berghei in infected mice and on promastigotes of Leishmania aethiopica, respectively. 1H-pyrazole can be used in research related to malaria and leishmaniasis .

HY-W001663R

4'-Hydroxy-3'-methylacetophenone (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Rubiaceae Phenols Plants Coffea arabica L. Source Classification	Reference Standards Bacterial
4'-Hydroxy-3'-methylacetophenone (Standard) is an analytical standard of 4'-Hydroxy-3'-methylacetophenone (HY-W001663). This product is intended for research and analytical applications. 4'-Hydroxy-3'-methylacetophenone is a phenolic volatile compound. 4'-Hydroxy-3'-methylacetophenone can be isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone is believed to possess potent antioxidant activity similar to that of other phenolic volatile compounds, Thymol (HY-N6810) and Eugenol (HY-N0337). 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N9998

Hirudonucleodisulfide A	Animals Ketones, Aldehydes, Acids Source Classification	Others
Hirudonucleodisulfide A is a heterocyclic compound that can be found in Whitmania pigra. Hirudonucleodisulfide A shows moderately anti-anoxic activity .

HY-147063R

N-Acetyl-α-D-glucosamine 1-phosphate disodium (Standard)	Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

Cat. No.	Product Name	Chemical Structure

HY-W355129S

MeIQx-d3
MeIQx-d3 is the deuterium labeled MeIQx (HY-W355129) . MeIQx is a heterocyclic amine (HAs) compound and a dietary aromatic amine, which can bind covalently to hemoglobin. MeIQx is a mutagenic compound that induces liver tumors .

HY-W017289S

4,4′-Dipyridyl-d8
4,4′-Dipyridyl-d₈ is the deuterium labeled 4,4'-Dipyridyl (HY-017289). 4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide.

HY-W779244

1H-Pyrazole-3,4,5-d3
1H-Pyrazole-3,4,5-d₃ is the deuterium labeled 1H-pyrazole (HY-76228). 1H-pyrazole is a nitrogen-containing heterocyclic compound composed of a five-membered ring and two nitrogen atoms. 1H-pyrazole is an intermediate in organic synthesis. 1H-pyrazole coordinates with metal ions. 1H-pyrazole derivatives have antibacterial, anti-inflammatory, anti-malarial, and anti-leishmanial activities .

HY-W713126

Indole-d4

Indole-d₄ is the deuterium labeled Indole (HY-W001132). Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

HY-W016825S1

2-(Pyridin-2-yl)acetic acid-d4 hydrochloride
2-(Pyridin-2-yl)acetic acid-d₄ hydrochloride is the deuterated derivative of 2-(Pyridin-2-yl)acetic acid hydrochloride (HY-W016825). 2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex.

HY-W699983

Imidazole-15N2

Imidazole- ¹⁵N₂ (Glyoxaline- ¹⁵N₂) is ¹⁵N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-Y0061S

Oxindole-d4
Oxindole-d₄ (2-Indolinone-d₄) is the deuterium labeled Oxindole (HY-Y0061). Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.

HY-W016825S

2-(Pyridin-2-yl)acetic acid-d6 hydrochloride
2-(Pyridin-2-yl)acetic acid-d₆ hydrochloride is the deuterated derivative of 2-(Pyridin-2-yl)acetic acid hydrochloride (HY-W016825). 2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex.

HY-W016825S2

2-(Pyridin-2-yl)acetic acid-d2 hydrochloride
2-(Pyridin-2-yl)acetic acid-d₂ hydrochloride is the deuterated derivative of 2-(Pyridin-2-yl)acetic acid hydrochloride (HY-W016825). 2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex.

HY-W007355S2

Skatole-13C6

Skatole- ¹³C₆ is the ¹³C-labeled Skatole (HY-W007355). Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream.

HY-Y0191S

α-Pyridone-d5
α-Pyridone-d₅ (2-Pyridone-d₅) is the deuterium labeled α-Pyridone (HY-Y0191). α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds .

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