271-44-3
271-44-3
Chemical Structure
Indazole
- CAS. Nr.: 271-44-3
- Formula:C7H6N2
- Molecular Weight:118.14
IUPAC Name: 1H-indazole
InChIKey: BAXOFTOLAUCFNW-UHFFFAOYSA-N
SMILES: C12=CC=CC=C1NN=C2
Biological Activity: Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases[1][2][3][4][5].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Indazole | 99.83% | Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Indazole (Standard) | ≥98% | Indazole (Standard) is the analytical standard of Indazole. This product is intended for research and analytical applications. Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Amino-1H-indazole | 99.35% | 5-Amino-1H-indazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
6-Bromo-1H-indazole | 99.40% | 6-Bromo-1H-indazole is an indazole derivative that serves as an intermediate for research related to organic synthesis. 6-Bromo-1H-indazole acts as a building block for the preparation of PI3Kδ inhibitors, and also functions as a synthetic intermediate for the preparation of colchicine site-targeted tubulin polymerization inhibitors. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Bromo-1H-indazole | 99.79% | 4-Bromo-1H-indazole is a carbonic anhydrase inhibitor, with an IC50 of 0.403 mM and a Ki of 0.383 mM against hCA-I, as well as an IC50 of 0.700 mM and a Ki of 0.935 mM against hCA-II. 4-Bromo-1H-indazole reduces the catalytic activity of human I and II isoforms of carbonic anhydrase. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
1H-Indazol-5-ol | 99.74% | 1H-Indazol-5-ol is a porcine DAAO inhibitor with an IC50 value of 2.03 μM. 1H-Indazol-5-ol can be used in the research of neurological disorders. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-Azaindazole | 1H-Pyrazolo[3,4-b]pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
6-Hydroxyindazole | 98.97% | 6-Hydroxyindazole is an anti-parasite agent with an EC50 of 128.9 μM against intracellular amastigotes of Leishmania amazonensis. 6-Hydroxyindazole can be used in the research of leishmaniasis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Indole-15N | 99.7% | Indole-15N is the 15N labeled Indole. Indole is an endogenous metabolite. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Azaindole | 99.92% | 1H-Pyrrolo[3,2-c]pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
1,2-Benzisoxazole | 98.00% | 1,2-Benzisoxazole (Indoxazene) is a potential substrate of rabbit liver aldehyde oxidase. 1,2-Benzisoxazole was used in the discovery and development of zonisamide (HY-B0124) for the study of epilepsy and Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzimidazole | 99.92% | Benzimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Shang C, et al. The Anticancer Activity of Indazole Compounds: A Mini Review. Curr Top Med Chem. 2021;21(5):363-376. [Content Brief]
- [2]. Pal D, et al. Importance of Indazole against Neurological Disorders. Curr Top Med Chem. 2022;22(14):1136-1151. [Content Brief]
- [3]. Uppulapu SK, et al. Indazole and its Derivatives in Cardiovascular Diseases: Overview, Current Scenario, and Future Perspectives. Curr Top Med Chem. 2022;22(14):1177-1188. [Content Brief]
- [4]. Saha S, et al. Indazole Derivatives Effective against Gastrointestinal Diseases. Curr Top Med Chem. 2022;22(14):1189-1214. [Content Brief]
- [5]. Qin J, et al. Indazole as a Privileged Scaffold: The Derivatives and their Therapeutic Applications. Anticancer Agents Med Chem. 2021;21(7):839-860. [Content Brief]
